AibGenesis™ Mouse Anti-GRX2 Antibody (CBMOAB-01583CR)

Name: AibGenesis™ Mouse Anti-GRX2 Antibody (CBMOAB-01583CR)
SKU: CBMOAB-01583CR
Rating: 5 (1 reviews)

Cat: CBMOAB-01583CR

Certificate of Analysis Lookup
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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-01583CR	Monoclonal	Yeast, Cucumber (Cucumis sativus)	WB, ELISA	MO01583CR		100 µg	Inquiry
Protein Refseq: The length of the protein is 143 amino acids long. The sequence is show below: METNFSFDSNLIVIIIITLFATRIIAKRFLSTPKMVSQETVAHVKDLIGQKEVFVAAKTYCPYCKATLSTLFQELNVPKSKALVLELDEMSNGSEIQDALEEISGQKTVPNVYINGKHIGGNSDLETLKKNGKLAEILKPVFQ.
MO-AB-28472W	Monoclonal	Cucumber (Cucumis sativus)	WB, ELISA	MO28472W		100 µg	Inquiry
Protein Refseq: The length of the protein is 125 amino acids long. The sequence is show below: MGSWFSSNKFSKEELELALNEVKKIVSTDPVVVFSKTYCGFCSSVKKLLTQLGARYKVIELDQKSDGDKIQSALAEWTGQTTVPNVFIGGKHIGGCDAVTEKHHRGQLVPLLTEAGAIAGNSAQL.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Yeast, Cucumber (Cucumis sativus)
Clone	MO01583CR
Specificity	This antibody binds to Yeast GRX2.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Mitochondrion; Other locations; Cytosol

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Component of the glutathione system which performs several activities such as glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity (PubMed:11875065, PubMed:12684511). The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. GRX2 is more active as an oxidoreductase than GRX1 (PubMed:9571241, PubMed:18992757, PubMed:20417731). Responsible for the S-glutathionylation of DHBP synthase (PubMed:21565288). (From uniprot, under CC BY 4.0)
Product Overview	Mouse Anti-Yeast GRX2 Antibody is a mouse antibody against GRX2. It can be used for GRX2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Glutaredoxin-2, mitochondrial; Glutathione-dependent oxidoreductase 2; Thioltransferase; GRX2; TTR TTR1; YDR513W
UniProt ID	P17695
Protein Refseq	The length of the protein is 143 amino acids long. The sequence is show below: METNFSFDSNLIVIIIITLFATRIIAKRFLSTPKMVSQETVAHVKDLIGQKEVFVAAKTYCPYCKATLSTLFQELNVPKSKALVLELDEMSNGSEIQDALEEISGQKTVPNVYINGKHIGGNSDLETLKKNGKLAEILKPVFQ.

For Research Use Only | Not For Clinical Use.

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