Mouse Anti-pabpc4 Antibody (CBMOAB-91228FYA)


Cat: CBMOAB-91228FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-91228FYA Monoclonal Zebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cattle (Bos taurus), Frog (Xenopus), Marmoset, Rhesus (Macaca mulatta) WB, ELISA MO91228FYA 100 µg
MO-AB-04961W Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO04961W 100 µg
MO-AB-05970H Monoclonal Frog (Xenopus laevis) WB, ELISA MO05970C 100 µg
MO-AB-20712W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO20712W 100 µg
MO-AB-60882W Monoclonal Marmoset WB, ELISA MO60882W 100 µg
MO-DKB-03371W Polyclonal Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cattle (Bos taurus), Frog (Xenopus), Zebrafish (Danio rerio) WB, IHC, IHC-P 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cattle (Bos taurus), Frog (Xenopus), Marmoset, Rhesus (Macaca mulatta)
CloneMO91228FYA
SpecificityThis antibody binds to Zebrafish pabpc4.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionPoly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (From NCBI)
Product OverviewMouse Anti-Zebrafish pabpc4 Antibody is a mouse antibody against pabpc4. It can be used for pabpc4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesPoly(A) binding protein, cytoplasmic 4; Inducible form; pabpc
UniProt IDQ7T3G5
Protein RefseqThe length of the protein is 637 amino acids long.
The sequence is show below: MNAATAGSYPMASLYVGDLHPDITEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVVKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQDAADRAIEKMNGMLLNDRKVFVGRFKSRKEREAEMGAKAKEFTNVYIKNFGDDMDDQRLKELFDKYGKTLSVKVMTDPTGKSRGFGFVSYEKHEDANKAVEEMNGTELNGKTVFVGRAQKKMERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEEGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRIAGMRAMPANAIINQFQPAGGYFMPAVPQAQNRTTYYAPNQLTQMRPNPRWQQQGGRGQGGFQGMPSSLRQPGPRANIRHLAPNASNQGPRGMPTGAQRVGGTGQPMGPRPAMGMTTPRAMPPYKYASTIRNTQPQVVQPIALQQAQPAVHVQGQEPLTASMLAAAPPQEQKQMLGERLFPLIQAMHPSLAGKITGMLLEIDNSELLHMLESHESLRSKVEEAVAVLQAHQAKKDATQKVGVTAATAAATS.
For Research Use Only | Not For Clinical Use.
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