Mouse Anti-tdg Antibody (CBMOAB-08963FYB)
Cat: CBMOAB-08963FYB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-08963FYB | Monoclonal | Zebrafish (Danio rerio), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Rhesus (Macaca mulatta) | WB, ELISA | MO08963FYB | 100 µg | ||
| CBMOAB-59955FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO59955FYA | 100 µg | ||
| MO-AB-08328H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO08328C | 100 µg | ||
| MO-AB-15573W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO15573W | 100 µg | ||
| MO-AB-21398R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO21398R | 100 µg | ||
| MO-AB-66015W | Monoclonal | Marmoset | WB, ELISA | MO66015W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Zebrafish (Danio rerio), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Rhesus (Macaca mulatta) |
| Clone | MO08963FYB |
| Specificity | This antibody binds to Zebrafish tdg. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. |
| Product Overview | Mouse Anti-Zebrafish tdg Antibody is a mouse antibody against tdg. It can be used for tdg detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Tdg protein; Thymine-DNA glycosylase; td |
| UniProt ID | Q503G3 |
| Protein Refseq | The length of the protein is 441 amino acids long. The sequence is show below: MDERLYGSLPHAPSEYLQQWVQSAQQHLQTLQAQYPHMANGSAGFMMEGQREDAGMQQMPVHPEDAAQLQPAAAQTAPAKGKRARQTNKEPKPKGEPKPRAKPGPKPKKAKEDKEAPPAEGQEKIDETFKKVKRKVDRFKGMSEEEVMKRTLPDILIPNLDYVIIGINPGLMAAYIGRWFPGPGNHFWKCLFLSGFTEKLLNHMDDQSLPEKYGIGFTNMVARATPGSKDLSSKELREGGKILVEKIKQFKPLIAVFNGKCIYEMFCRELFGKKPKTLEFGLQPHKIPDSDTALYLMPSSSARCAQFPRAQDKVHFYIKLRELRDQLKGVIKQKEVEEVNYTFDLGLAKEDAKRIAVKEEQYDPGYEAAFGGAYGEAAPEGGQSNGICNFSASEENANTAEKAPTKPSDVGQVQDGQWMTQSFADQIPDIGSSSQAQNWGV. |
For Research Use Only | Not For Clinical Use.
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