Mouse Anti-ubr3 Antibody (CBMOAB-11583FYB)


Cat: CBMOAB-11583FYB
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Lot Number

  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-11583FYB Monoclonal Zebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Marmoset, Rhesus (Macaca mulatta) WB, ELISA MO11583FYB 100 µg
CBMOAB-61741FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO61741FYA 100 µg
MO-AB-03259W Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO03259W 100 µg
MO-AB-10262W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO10262W 100 µg
MO-AB-67341W Monoclonal Marmoset WB, ELISA MO67341W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio), Chimpanzee (Pan troglodytes), Fruit fly (Drosophila melanogaster), Marmoset, Rhesus (Macaca mulatta)
CloneMO11583FYB
SpecificityThis antibody binds to Zebrafish ubr3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionE3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May play a role in Shh signaling by mediating the ubiquitination of Kif7. May be important for MYH9 function in certain tissues, possibly by regulating the ubiquitination of MYH9 and consequently affecting its interaction with MYO7A (PubMed:27331610). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-Zebrafish ubr3 Antibody is a mouse antibody against ubr3. It can be used for ubr3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Namesubr3; Ubiquitin Protein Ligase E3 Component N-Recognin 3 (Putative)
UniProt IDF1QJX5
Protein RefseqThe length of the protein is 954 amino acids long.
The sequence is show below: IWMDHQNMSEHVLCMVLYLIELGLDNQVQDDKVEEEPCIEEHCHDSWFPGTSLLSNLHHVINFVRVRVPETAPEVERKRERERERETPPSTSSESATFGQNLREAQVFSLVAERRRKFQEIINRSNHEASQAVRPKSSASRWLPPGTPPQLVTEILEIRESMLSLLVKLHQKLSAKQNSLSLSWLAEVDPAHHAHGDGLTAIERILAKASARSRHSKRCLQEICGKVCPPIPPKKISPGDKKSMDKEERRQRARERQQKLLAEFASRQKSFMETAMDVESPEADAVMDVSSEESLDSEVLYDCVICGQSGPSTEDRPTGLVVLLQASSVLGHRCRSDMPKRLPTTDEEHIYPEDTCGATHDVRLSLMQRYFKDSSCLQSVSIGWDGGVYVQTCGHTLHIDCHKSYMESLRNDQVLQGISVDKGEFTCPLCRQFANSVLPCRPGRGMETGAWHAPSTKSMSTLVKEVEDLQEQLGIFPIESNLSKEMESVIKDIKNTTQKKYMDYGKNPGSPDNDFLFMYSVARTNLELELVHRGGNLCSGGASAAAKRSCLNQLFHVLAMHMRLYSIDSAYNPWTRLTLSTQSRENEYCDEERPEVPMLFRDVPSLLIIFILTMPQPLRKEHFTCVVKVLYSLQFTQALAALSIRFSREERLAWSNTGAAKKNLPNSDKSWESLLGHMISELTKAKDVYDTNSEETSALSSSVWSPQSIEFRLQQFCLPFLRLSCLLQHHLYGDSLPGCLVEEEFSLLTRCLGLAASVQCSGSMSSAACLEWNISAFDLISQWCSEVVALSDTPSQQSASLLGQDPQWAAPRLLQLPDNYNTIFQYYHRKSCSSCGKTPKDPALCLVCGAFVCLKGHCCKQQGVCECVLHSQHCGAATGIFLLINASVIIIIRGHRFCLWGSVYLDAHGEEDRDLRRGKPLYLCEERYRVLEQQWVAHTFDHINKRWGPHYNGL.
For Research Use Only | Not For Clinical Use.
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