Certificate of Analysis Lookup
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Protein Refseq: The length of the protein is 1040 amino acids long. The sequence is show below: MIAEKPFWVKHEGLQIFSIDVQPNGERFATGGGDHKVRIWNMKSVDKDLQNIDTKERLLATLRDHFGSVNCVRWAKNSRYVASGSDDQVIQIHERKPGSGTTEFGSGEAPDVENWKAVMTLRGHTADVVDLNWSPDDSMLASGSLDNTVHIWNMRTGMCTTVLRGHLSLVKGVTWDPIGSFIASQSDDKTVIIWRTSDWGMAHRTDGHWAKSLGSTFFRRLGWSPCGHFLTTTHGFQKPKHSAPVLERGEWSVAYDFLGHSAPIIVVRFNHSMFKRIPSSTHETKQVGWSNGTSKSGEKDLQSYNVIAMGSQDRTITVWTTGSARPLFVAKHFFGQSVVDLSWSPDGYSLFACSLDGTVAMIHFDPKELGVRLTDTELDELKKSRYGDVRGRQANLVESPAQLLLETASTKQAGSKRAASDVQQNQVTTKPSVSVESTAKRRKSQVDDRNKAAESTGQTLNKASTLNRVSSPVNQKVYRRPDGRKRIIPEAVGVPQQENNIMINGESHNFLPASAAAPAKGDSGDFPVEISNRDLSGKEIVCRNPDLKERSRITARATITESLVIEKVPGTSGRDGVLNVEQSVGIKESSSTDLLIRVFDWKDGEAAPPVCLEACPREHALDTVGAVSTSMVKETEISCKKSGETLWSDRIMGRVTVLAGNPNFWAAGCEDGSLQVYTKCGRRAMPTMMMGSAATFIDCDDSWKLLLVTRKGSLYVWDLFNRKCVLHDSLSSLVSSDVNLSSTVKVELLSWYEDSSVIDLDCTIKVISVKLSKSGSPLVVLATRHAFLFDTSLMCWLRVADDCFPASNFSSSWNLGSAPCGELAGLQVDVRKYMARKPGWNRITDDGTQTRAHLESQLASSLALESPNEYRQCLLAYVRFLAREADESRLREVCESFLGPPTGMAEAASSDTNLSWDPYVLGVKKHKLLRNDILPAMASNRKVQRLLNEFIDLLSEYEDVETADPAPKGSTPTMNCGGVPSSLDQIGSDPPAMTATTPMTIDNDKPVSLENPAALDIGVCEKTGSEDRDKQDQNSRDSGS.
Protein Refseq: The length of the protein is 1047 amino acids long. The sequence is show below: MRLLKPAWVHHDDKQIFSVDIHKDCTKFATGGQGSDCGRVVIWNLLPVLSDKAEFDADVPKMLCQMDQHLACVNCVRWSQNGQNLASGSDDKLIMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSPNDVYLASCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIWNTMNWSLSHTITEPFEECGGTTHILRLSWSPDGQYLVSAHAMNGGGPTAQIIEREGWKCDKDFVGHRKAVTCVRFHNSILSRQENDGSPSKPLQYCCLAVGSRDRSLSVWMTALQRPMVVIHELFNASILDLTWGPQECLLMACSVDGSIACLKFTEEELGKAISEEEQNAIIRKMYGKNYVNGLGKSAPVLEHPQRLLLPQGDKPTKFPLSNNNEANQRPISKQTETRTKDGKRRITPMFIPLHEDGPTSLSMNIVSSSGSSTTALTSCSAAIGTLPAAAPTESAATPLMPLEPLVSKIDLGRLDSRLKTQPASQRRQSLPFDPGQSNELLRTPRLEEHQSSTCSPSNLNVTATGKSEFVKAALDYRLHVSNGHLKTQHGMLAKVTASDSKEMLWEFYVGSPLVNLNLCEKYAMLCSLDGSMRLISMETGCPVFPAISLTSSAVHCAFSPDNSLVGVLTECGLLRIWDIAKKVVSLAAGCLELLNKHGTAAQFSVTNQGMPLIGFPSGNSYSYSTSLQSWLVLATKDAIMYHGIRGTLPRDMDQMQQKFPLLSMQASSQNYFSFTGSMELRHSESWQQCAKIRFIENQIKLCEALQSLDELQHWHKMLTFQLATHGSEKRMRVFLDDLLSMPEPGISQFVPKLELMQCVLDTLKPHSEWNRLHSEYTELLKECKSERQKDIFATPAPPQQKTASSAGSSPRSGEATGEEVTEKDGATAVAAAVVAGSRMAVTTGTSTTTTTTASSSLSSSGSSSSTSGSGSSSSSSSTSSLSVPQPAPSLSPEIQTLDSPTVCIDDEILSASSSLPPLDTSPVEVSPASTSGGAASTSPAASVAGSAPVSSSKTDQT.
Protein Refseq: The length of the protein is 679 amino acids long. The sequence is show below: DVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQQLDQKSAATREMGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSGSLAGTMLSSHSSPQLLPLDSSTPNSFGASKPCTEPVVAASARPAGDSVNKDSMNATSTPAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSVTPTAAERDVHRQVVVVKEESLHSILAGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK.
Protein Refseq: The length of the protein is 1010 amino acids long. The sequence is show below: MKLLKPSWVNHNGKPIFSVDIHPDGTKFATGGQGEDSGKVVIWNMAPVLREEDEKNENIPKLLCQMDNHLACVNCVRWSNNGLYLASGGDDKLVMVWKRAAFIGPSTVFGSSSKLANVEQWRCVTILRNHTGDVMDVAWSPHDVWLASCSVDNTIVIWNARKFPEIVMTLKGHTGLVKGLTWDPVGKYIASQADDHSLKVWRTMDWQLETNITKPFSECGGTTHVLRLSWSPDGQYLVSAHAMNNSGPTAQIIERDGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSTPKPSCPYCCCAVGSKDRSLSVWLTSLKRPLVVIHDLFDKSIMDITWTLNGLGLLVCSMDGTVAFLDFSQDELGDPLNEEEKNAIHQNIYGKSLAITMESQLSTTIIENPEMLKYQQERQGNQNANVAQGSGPENQTPKLTNVLNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSPALFNSVPILPGSSASTQLTPQISSDSNTANSLGLRPSHDPSTTSPNKTAEENKDSATAPVNSIGMKSTLLLTSASKIEPMKALDSRFTERSKATPGVTSVPITIGITPLDRAKDSSSVKEPKGKDETSSDSEDKIMNKTLSMAKRKGEIEGGEVVEKRKKGRPRKDAKMMMPISQPFPQTPVSVKEELPRLATPAVVLKLPTPSIQKSFSTQVGTDAVTYLEVENEVSVVSGARLSQLKWRREGREWDTLLPSRIIIATGSSDVVAVACEDRTLSVFTACGRRLIPSIMLPAPMSALHCSGHFVMALMASATLSVWDVQKQTALVKNESLNPILSGTDATVSQSLITQQGVAVVSLSNGKTYCFNSSLETWNLIADKQDSLVQCADFRNCLSSQDVLGSMGPLALTQGRNLSAGRLASRLSSTPHHLQQGMTLAFLENQLSSALMLLSASEYRHWLLIYARFLVNEGYEHRLRELCQDLLGPVHKSSSSSWESTVLGLRKRDLLTEVLPVIGQNLRFQRLFTEYQDQLELLRLK.
Protein Refseq: The length of the protein is 1017 amino acids long. The sequence is show below: MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSAKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLDQKSAATREMGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSGSLAGTMLSSHSSPQLLPLDSSTPNSFGASKPCTEPVVAASARPAGDSVNKDSMNATSTPAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSMTPTAVERLKEQNLVKELRPRDLLESSSDSDEKVPLAKASSLSKRKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPAALTAEKEAMCLSAPALALKLPIPGPQRAFTLQVSSDPSMYIEVENEVTVVGGVKLSRLKCNREGKEWETVLTSRILTAAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTLHCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLVYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK.
Protein Refseq: The length of the protein is 1017 amino acids long. The sequence is show below: MKLLKPTWVNHNGKPIFSVDIHPDGTKFATGGQGQDSGKVVIWNMSPVLQEDDEKDENIPKMLCQMDNHLACVNCVRWSNSGMYLASGGDDKLIMVWKRATYIGPSTVFGSSGKLANVEQWRCVSILRNHSGDVMDVAWSPHDAWLASCSVDNTVVIWNAVKFPEILATLRGHSGLVKGLTWDPVGKYIASQADDRSLKVWRTLDWQLETSITKPFDECGGTTHVLRLSWSPDGHYLVSAHAMNNSGPTAQIIEREGWKTNMDFVGHRKAVTVVKFNPKIFKKKQKNGSSTKPSCPYCCCAVGSKDRSLSVWLTCLKRPLVVIHELFDKSIMDISWTLNGLGILVCSMDGSVAFLDFSQDELGDPLSEEEKSRIHQSTYGKSLAIMTEAQLSTAVIENPEMLKYQRRQQQQQLEQKSASTRETGSATSVAGVVNGESLEDIRKNLLKKQVETRTADGRRRITPLCIAQLDTGDFSTAFFNSIPLSGSLAGTMLSSHSSPQLLPLDSSTPNSFGASKPCTEPVVAASARPAGDSVNKDSMNATSTPAALSPSVLTTPSKIEPMKAFDSRFTERSKATPGAPALTSVTPTAMERLKEQNLVKELRPRDLLESSSDSDEKVPLTKPSSLSKRKLELEVETVEKKKKGRPRKDSRLMPVSLSVQSPATLTAEKEAMCLSAPALALKLPIPGPQRAFTLQVSSDPSMYIEVENEVTVVGGVKLSRLKCNREGKEWETVLTSRILTAAGSCDVVCVACEKRMLSVFSTCGRRLLSPILLPSPISTLHCTGSYVMALTAAATLSVWDVHRQVVVVKEESLHSILAGSDMTVSQILLTQHGIPVMNLSDGKAYCFNPSLSTWNLVSDKQDSLAQCADFRSSLPSQDAMLCSGPLAIIQGRTSNSGRQAARLFSVPHVVQQETTLAYLENQVAAALTLQSSHEYRHWLLLYARYLVNEGFEYRLREICKDLLGPVHYSTGSQWESTVVGLRKRELLKELLPVIGQNLRFQRLFTECQEQLDILRDK.
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Application Information
Application
WB, IHC
Application Notes
WB: 1:500-1:2000 IHC: 1:50-1:200 Other applications are to be developed. The optimal dilution should be determined by the end user.
Target
Introduction
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
Product Overview
This product is a Mouse antibody against the HIRA. It can be used for HIRA antibody detection in Western Blot, Immunohistochemistry.
Alternative Names
Histone Cell Cycle Regulator; TUP1-Like Enhancer Of Split Protein 1; DiGeorge Critical Region Gene 1; TUPLE1; DGCR1; HIR (Histone Cell Cycle Regulation Defective) Homolog A (S. Cerevisiae)
