Mouse Anti-Yeast Atg8 Antibody (MOFAB-740W)
Cat: MOFAB-740W
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse |
| Species Reactivity | Yeast |
| Immunogen | Atg8 Antibody detects endogenous levels of total Atg8. |
| Format | Liquid or Lyophilized |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | WB, IHC, IF |
| Application Notes | WB: 1:1000-1:2000 IHC/IF: 1:100-1:1000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Ubiquitin-like modifiers are involved in autophagosome formation. Mediates autophagosome delivery to vacuoles through the microtubule cytoskeleton using ATG4. Selective autophagic degradation of the nucleus (nucleophagy) and required for mitophagy, which helps to regulate mitochondrial quantity and quality by eliminating mitochondria to basal levels to meet cellular energy demands and prevent excess ROS production. Also involved in membrane fusion events that occur in the early secretory pathway. It is also involved in the endoplasmic reticulum-specific autophagy process and is essential for the survival of cells subjected to severe ER stress. The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, resulting in the expansion of the autophagosome membrane during autophagy. |
| Product Overview | This product is a Mouse antibody against the Atg8. It can be used for Atg8 antibody detection in Western Blot, Immunohistochemistry, Immunofluorescence. |
| Alternative Names | Autophagy-related protein 8; Autophagy-related ubiquitin-like modifier ATG8; Pexophagy zeocin-resistant mutant protein 2; PAZ2; |
| UniProt ID | Q8NJJ4 |
See other products for " ATG8 "
| MO-DKB-0063RA | Rabbit Anti-ATG8 Antibody (MO-DKB-0063RA) |
| CBMOAB-00395CR | Mouse Anti-Yeast ATG8 Antibody (CBMOAB-00395CR) |
| MO-DKB-03765W | Rabbit Anti-ATG8 Antibody (Cat MO-DKB-03765W) |
For Research Use Only | Not For Clinical Use.
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