ATP-binding cassette transporter 1

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

  • Mouse Anti-ABCA1 Antibody (CBMOAB-1248FYC) (CAT#: CBMOAB-1248FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Horse (Equus caballus), Marmoset, Pig (Sus scrofa), Rat (Rattus norvegicus), Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Submitted name: ATP-binding cassette A1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: ATP Binding Cassette Subfamily A Member 1, ATP-Binding Cassette, Sub-Family A (ABC1), Member 1, Cholesterol Efflux Regulatory Protein, ABC-1, ABC1, CERP, ATP-Binding Cassette Sub-Family A Member 1, ATP-Binding Cassette Transporter A1, ATP-Binding Cassette Transporter 1, ATP-Binding Cassette 1
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