APC2, WNT Signaling Pathway Regulator
This gene encodes a strongly conserved protein that has an N-terminal coiled-coil domain followed by an armadillo domain, five 20-amino acid repeats, and two SAMP domains. This protein promotes the assembly of a multiprotein complex that recruits and phosphorylates the Wnt effector beta-catenin and targets beta-catenin for ubiquitylation and proteasomal degradation. This protein therefore plays a role in the reduction of cytoplasmic levels of beta-catenin which in turn reduces activation of Wnt target genes that play a pivotal role in the pathogenesis of various human cancers. The protein encoded by this gene is closely related to the adenomatous polyposis coli (APC) tumor-suppressor protein and has similar tumor-suppressor effects. This gene also plays a role in actin assembly, cell-cell adhesion, and microtubule network formation through its interaction with cytoskeletal proteins. This gene has its highest expression in the central nervous system and is involved in brain development through cytoskeletal regulation in neurons. Alternative splicing produces multiple transcript variants encoding distinct isoforms.
Mouse Anti-Yeast APC2 Antibody (CBMOAB-00246CR) (CAT#: CBMOAB-00246CR)
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- Host species: Mouse
- Species Reactivity: Yeast
- Application: WB, ELISA
- Protein: Anaphase-promoting complex subunit 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Anaphase-promoting complex subunit 2, APC2, RSI1, YLR127C
Mouse Anti-C. elegans APC2 Antibody (CBMOAB-00557HCB) (CAT#: CBMOAB-00557HCB)
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- Host species: Mouse
- Species Reactivity: C. elegans (Caenorhabditis elegans)
- Application: WB, ELISA
- Protein: Anaphase-promoting complex subunit 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Anaphase-promoting complex subunit 2, APC2, Cyclosome subunit 2, apc-2
Mouse Anti-Arabidopsis APC2 Antibody (CBMOAB-2256FYC) (CAT#: CBMOAB-2256FYC)
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- Host species: Mouse
- Species Reactivity: A. thaliana (Arabidopsis thaliana)
- Application: WB, ELISA
- Protein: Anaphase-promoting complex subunit 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
- Alternative Names: APC2, WNT Signaling Pathway Regulator, Adenomatous Polyposis Coli Like, Adenomatosis Polyposis Coli 2, APCL, Adenomatous Polyposis Coli Protein-Like, Adenomatous Polyposis Coli Protein 2, APC-Like
Mouse Anti-Rhesus APC2 Antibody (CBMOAB-35988FYA) (CAT#: CBMOAB-35988FYA)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: Adenomatous polyposis coli protein 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Adenomatous polyposis coli protein 2, APC2
Mouse Anti-Arabidopsis APC2 Antibody (MO-AB-00070H) (CAT#: MO-AB-00070H)
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- Host species: Mouse
- Species Reactivity: Arabidopsis (Arabidopsis lyrata)
- Application: WB, ELISA
- Protein: Anaphase-promoting complex subunit 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Anaphase-promoting complex/cyclosome 2, APC2
Mouse Anti-Rhesus APC2 Antibody (MO-AB-03375W) (CAT#: MO-AB-03375W)
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- Host species: Mouse
- Species Reactivity: Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: APC regulator of WNT signaling pathway 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: APC2, WNT Signaling Pathway Regulator, Adenomatous Polyposis Coli Like, Adenomatosis Polyposis Coli 2, APCL, Adenomatous Polyposis Coli Protein-Like, Adenomatous Polyposis Coli Protein 2, APC-Like
Mouse Anti-Pig APC2 Antibody (MO-AB-23784R) (CAT#: MO-AB-23784R)
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- Host species: Mouse
- Species Reactivity: Pig (Sus scrofa)
- Application: WB, ELISA
- Protein: Submitted name: Adenomatous polyposis coli 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Adenomatous polyposis coli 2, APC2
Mouse Anti-Marmoset APC2 Antibody (MO-AB-51067W) (CAT#: MO-AB-51067W)
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- Host species: Mouse
- Species Reactivity: Marmoset
- Application: WB, ELISA
- Protein: Submitted name: Adenomatous polyposis coli protein 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Adenomatous polyposis coli protein 2, APC2
Rabbit Anti-APC2 Antibody (MO-DKB-02296W) (CAT#: MO-DKB-02296W)
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- Host species: Rabbit
- Species Reactivity: A. thaliana (Arabidopsis thaliana)
- Application: IP, IF
- Protein: Anaphase-promoting complex subunit 2
- Size: 150µg
- Conjugate: NONE
- Alternative Names: APC2, WNT Signaling Pathway Regulator, Adenomatous Polyposis Coli Like, Adenomatosis Polyposis Coli 2, APCL, Adenomatous Polyposis Coli Protein-Like, Adenomatous Polyposis Coli Protein 2, APC-Like, APC2, ANAPHASE-PROMOTING COMPLEX/CYCLOSOME 2, APC2.
Mouse Anti-D. melanogaster Apc2 Antibody (CBMOAB-01095FYA) (CAT#: CBMOAB-01095FYA)
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- Host species: Mouse
- Species Reactivity: Fruit fly (Drosophila melanogaster)
- Application: WB, ELISA
- Protein: Submitted name: LD24920p
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: LD24920p, Apc2
Mouse Anti-Zebrafish apc2 Antibody (CBMOAB-66104FYA) (CAT#: CBMOAB-66104FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Submitted name: APC regulator of WNT-signaling pathway 2
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: apc2, APC2, WNT Signaling Pathway Regulator
For Research Use Only | Not For Clinical Use.
