APC2, WNT Signaling Pathway Regulator

This gene encodes a strongly conserved protein that has an N-terminal coiled-coil domain followed by an armadillo domain, five 20-amino acid repeats, and two SAMP domains. This protein promotes the assembly of a multiprotein complex that recruits and phosphorylates the Wnt effector beta-catenin and targets beta-catenin for ubiquitylation and proteasomal degradation. This protein therefore plays a role in the reduction of cytoplasmic levels of beta-catenin which in turn reduces activation of Wnt target genes that play a pivotal role in the pathogenesis of various human cancers. The protein encoded by this gene is closely related to the adenomatous polyposis coli (APC) tumor-suppressor protein and has similar tumor-suppressor effects. This gene also plays a role in actin assembly, cell-cell adhesion, and microtubule network formation through its interaction with cytoskeletal proteins. This gene has its highest expression in the central nervous system and is involved in brain development through cytoskeletal regulation in neurons. Alternative splicing produces multiple transcript variants encoding distinct isoforms.

Cat# Product Name Host species Species Reactivity Application Size Conjugate Alternative Names Protein
CBMOAB-00246CR Mouse Anti-Yeast APC2 Antibody (CBMOAB-00246CR) Mouse Yeast WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Anaphase-promoting complex subunit 2, APC2, RSI1, YLR127C Anaphase-promoting complex subunit 2
CBMOAB-00557HCB Mouse Anti-C. elegans APC2 Antibody (CBMOAB-00557HCB) Mouse C. elegans (Caenorhabditis elegans) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Anaphase-promoting complex subunit 2, APC2, Cyclosome subunit 2, apc-2 Anaphase-promoting complex subunit 2
CBMOAB-2256FYC Mouse Anti-Arabidopsis APC2 Antibody (CBMOAB-2256FYC) Mouse A. thaliana (Arabidopsis thaliana) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP APC2, WNT Signaling Pathway Regulator, Adenomatous Polyposis Coli Like, Adenomatosis Polyposis Coli 2, APCL, Adenomatous Polyposis Coli Protein-Like, Adenomatous Polyposis Coli Protein 2, APC-Like Anaphase-promoting complex subunit 2
CBMOAB-35986FYA Mouse Anti-Rhesus APC2 Antibody (CBMOAB-35986FYA) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Adenomatous polyposis coli protein 2, APC2 Submitted name: Adenomatous polyposis coli protein 2
CBMOAB-35987FYA Mouse Anti-Rhesus APC2 Antibody (CBMOAB-35987FYA) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Adenomatous polyposis coli protein 2, APC2 Submitted name: Adenomatous polyposis coli protein 2
CBMOAB-35988FYA Mouse Anti-Rhesus APC2 Antibody (CBMOAB-35988FYA) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Adenomatous polyposis coli protein 2, APC2 Submitted name: Adenomatous polyposis coli protein 2
MO-AB-00070H Mouse Anti-Arabidopsis APC2 Antibody (MO-AB-00070H) Mouse Arabidopsis (Arabidopsis lyrata) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Anaphase-promoting complex/cyclosome 2, APC2 Anaphase-promoting complex subunit 2
MO-AB-03375W Mouse Anti-Rhesus APC2 Antibody (MO-AB-03375W) Mouse Rhesus (Macaca mulatta) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP APC2, WNT Signaling Pathway Regulator, Adenomatous Polyposis Coli Like, Adenomatosis Polyposis Coli 2, APCL, Adenomatous Polyposis Coli Protein-Like, Adenomatous Polyposis Coli Protein 2, APC-Like Submitted name: APC regulator of WNT signaling pathway 2
MO-AB-23784R Mouse Anti-Pig APC2 Antibody (MO-AB-23784R) Mouse Pig (Sus scrofa) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Adenomatous polyposis coli 2, APC2 Submitted name: Adenomatous polyposis coli 2
MO-AB-51067W Mouse Anti-Marmoset APC2 Antibody (MO-AB-51067W) Mouse Marmoset WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Adenomatous polyposis coli protein 2, APC2 Submitted name: Adenomatous polyposis coli protein 2
MO-DKB-02296W Rabbit Anti-APC2 Antibody (MO-DKB-02296W) Rabbit A. thaliana (Arabidopsis thaliana) IP, IF 150µg NONE APC2, WNT Signaling Pathway Regulator, Adenomatous Polyposis Coli Like, Adenomatosis Polyposis Coli 2, APCL, Adenomatous Polyposis Coli Protein-Like, Adenomatous Polyposis Coli Protein 2, APC-Like, APC2, ANAPHASE-PROMOTING COMPLEX/CYCLOSOME 2, APC2. Anaphase-promoting complex subunit 2
CBMOAB-01095FYA Mouse Anti-D. melanogaster Apc2 Antibody (CBMOAB-01095FYA) Mouse Fruit fly (Drosophila melanogaster) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP LD24920p, Apc2 Submitted name: LD24920p
CBMOAB-01096FYA Mouse Anti-D. melanogaster Apc2 Antibody (CBMOAB-01096FYA) Mouse Fruit fly (Drosophila melanogaster) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP Adenomatous polyposis coli 2, Adenomatous polyposis coli tumor suppressor homolog 2, Epithelial adenomatous polyposis coli, Apc2, E-APC Submitted name: Adenomatous polyposis coli 2
CBMOAB-66104FYA Mouse Anti-Zebrafish apc2 Antibody (CBMOAB-66104FYA) Mouse Zebrafish (Danio rerio) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP apc2, APC2, WNT Signaling Pathway Regulator Submitted name: APC regulator of WNT-signaling pathway 2
CBMOAB-66105FYA Mouse Anti-Zebrafish apc2 Antibody (CBMOAB-66105FYA) Mouse Zebrafish (Danio rerio) WB, ELISA 0.5mg, 1mg, 200µg Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP apc2, APC2, WNT Signaling Pathway Regulator
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