BRCA1 homologue

This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified.

  • Mouse Anti-Arabidopsis BRCA1 Antibody (CBMOAB-25468FYC) (CAT#: CBMOAB-25468FYC)

    • Host species: Mouse
    • Species Reactivity: A. thaliana (Arabidopsis thaliana)
    • Application: WB, ELISA
    • Protein: Protein BREAST CANCER SUSCEPTIBILITY 1 homolog
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, None, PE, PerCP
    • Alternative Names: BRCA1, DNA Repair Associated, Protein Phosphatase 1, Regulatory Subunit 53, BRCA1/BRCA2-Containing Complex, Subunit 1, Fanconi Anemia, Complementation Group S, Breast Cancer 1, Early Onset, RING Finger Protein 53, RNF53, Breast And Ovarian Cancer Susceptibility Protein 1, Breast Cancer Type 1 Susceptibility Protein, RING-Type E3 Ubiquitin Transferase BRCA1, Early Onset Breast Cancer 1, Breast Cancer 1
  • Mouse Anti-Rhesus BRCA1 Antibody (CBMOAB-37078FYA) (CAT#: CBMOAB-37078FYA)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: RING-type E3 ubiquitin transferase BRCA1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast cancer type 1 susceptibility protein homolog, BRCA1
  • Mouse Anti-Chicken BRCA1 Antibody (MO-AB-00898Y) (CAT#: MO-AB-00898Y)

    • Host species: Mouse
    • Species Reactivity: Chicken (Gallus gallus)
    • Application: WB, ELISA
    • Protein: RING-type E3 ubiquitin transferase BRCA1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast and ovarian cancer susceptibility-like protein, BRCA1
  • Mouse Anti-Rhesus BRCA1 Antibody (MO-AB-01319W) (CAT#: MO-AB-01319W)

    • Host species: Mouse
    • Species Reactivity: Rhesus (Macaca mulatta)
    • Application: WB, ELISA
    • Protein: Breast cancer type 1 susceptibility protein homolog
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast cancer type 1 susceptibility protein isoform 1, BRCA1
  • Mouse Anti-Rabbit BRCA1 Antibody (MO-AB-07366Y) (CAT#: MO-AB-07366Y)

    • Host species: Mouse
    • Species Reactivity: Rabbit (Oryctolagus cuniculus)
    • Application: WB, ELISA
    • Protein: Submitted name: Breast and ovarian cancer susceptibility 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast and ovarian cancer susceptibility 1, BRCA1
  • Mouse Anti-Cattle BRCA1 Antibody (MO-AB-09116R) (CAT#: MO-AB-09116R)

    • Host species: Mouse
    • Species Reactivity: Cattle (Bos taurus)
    • Application: WB, ELISA
    • Protein: Breast cancer type 1 susceptibility protein homolog
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast cancer type 1 susceptibility protein homolog, BRCA1
  • Mouse Anti-Sheep BRCA1 Antibody (MO-AB-14401Y) (CAT#: MO-AB-14401Y)

    • Host species: Mouse
    • Species Reactivity: Sheep (Ovis aries)
    • Application: WB, ELISA
    • Protein: Submitted name: BRCA1 homologue
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: BRCA1 homologue, BRCA1
  • Mouse Anti-Chimpanzee BRCA1 Antibody (MO-AB-15024W) (CAT#: MO-AB-15024W)

    • Host species: Mouse
    • Species Reactivity: Chimpanzee (Pan troglodytes)
    • Application: WB, ELISA
    • Protein: Breast cancer type 1 susceptibility protein homolog
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast cancer 1, early onset, BRCA1
  • Mouse Anti-Pig BRCA1 Antibody (MO-AB-24182R) (CAT#: MO-AB-24182R)

    • Host species: Mouse
    • Species Reactivity: Pig (Sus scrofa)
    • Application: WB, ELISA
    • Protein: RING-type E3 ubiquitin transferase BRCA1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast cancer type 1 susceptibility protein homolog, Fragment, BRCA1
  • Mouse Anti-Dog BRCA1 Antibody (MO-AB-29265W) (CAT#: MO-AB-29265W)

    • Host species: Mouse
    • Species Reactivity: Dog (Canis lupus familiaris)
    • Application: WB, ELISA
    • Protein: Breast cancer type 1 susceptibility protein homolog
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast cancer type 1 susceptibility protein homolog, BRCA1
  • Mouse Anti-Donkey BRCA1 Antibody (MO-AB-34168W) (CAT#: MO-AB-34168W)

    • Host species: Mouse
    • Species Reactivity: Donkey (Equus asinus)
    • Application: WB, ELISA
    • Protein: Submitted name: BRCA1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: BRCA1, BRCA1
  • Mouse Anti-Hamsters BRCA1 Antibody (MO-AB-42966W) (CAT#: MO-AB-42966W)

    • Host species: Mouse
    • Species Reactivity: Hamsters (Cricetinae)
    • Application: WB, ELISA
    • Protein: Submitted name: Breast and ovarian cancer susceptibility 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast and ovarian cancer susceptibility 1, BRCA1
  • Mouse Anti-Horse BRCA1 Antibody (MO-AB-43866W) (CAT#: MO-AB-43866W)

    • Host species: Mouse
    • Species Reactivity: Horse (Equus caballus)
    • Application: WB, ELISA
    • Protein: Submitted name: BRCA1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: BRCA1
  • Mouse Anti-Marmoset BRCA1 Antibody (MO-AB-51933W) (CAT#: MO-AB-51933W)

    • Host species: Mouse
    • Species Reactivity: Marmoset
    • Application: WB, ELISA
    • Protein: Submitted name: Breast and ovarian cancer susceptibility 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast and ovarian cancer susceptibility 1, BRCA1
  • Mouse Anti-Frog brca1 Antibody (MO-AB-01921H) (CAT#: MO-AB-01921H)

    • Host species: Mouse
    • Species Reactivity: Frog (Xenopus laevis)
    • Application: WB, ELISA
    • Protein: RING-type E3 ubiquitin transferase BRCA1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast and ovarian cancer susceptibility protein, brca1, BRCA1
  • Mouse Anti-Purple sea urchin brca1 Antibody (MO-AB-30602H) (CAT#: MO-AB-30602H)

    • Host species: Mouse
    • Species Reactivity: Purple sea urchin (Strongylocentrotus purpuratus)
    • Application: WB, ELISA
    • Protein: RING-type E3 ubiquitin transferase BRCA1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: BRCA1, brca1
  • Mouse Anti-Ferret brca1 Antibody (MO-AB-34462W) (CAT#: MO-AB-34462W)

    • Host species: Mouse
    • Species Reactivity: Ferret (Mustela Putorius Furo)
    • Application: WB, ELISA
    • Protein: Submitted name: Breast and ovarian cancer susceptibility protein 1
    • Size: 0.5mg, 1mg, 200µg
    • Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
    • Alternative Names: Breast and ovarian cancer susceptibility protein 1, brca1
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