Histone-lysine N-methyltransferase, H3 lysine-79 specific
Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
Mouse Anti-DOT1L Antibody (MO-AB-01640Y) (CAT#: MO-AB-01640Y)
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- Host species: Mouse
- Species Reactivity: Chicken (Gallus gallus), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Guinea pig (Cavia porcellus), Horse (Equus caballus), Marmoset, Medaka (Oryzias latipes), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries)
- Application: WB, ELISA
- Protein: Histone-lysine N-methyltransferase, H3 lysine-79 specific
- Size: 0.5mg, 1mg, 200µg
- Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Histone-lysine N-methyltransferase, H3 lysine-79 specific, EC 2.1.1.43, Histone H3-K79 methyltransferase, DOT1L
Mouse Anti-dot1l Antibody (CBMOAB-74015FYA) (CAT#: CBMOAB-74015FYA)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Guinea pig (Cavia porcellus), Horse (Equus caballus), Marmoset, Medaka (Oryzias latipes), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries)
- Application: WB, ELISA
- Protein: Histone-lysine N-methyltransferase, H3 lysine-79 specific
- Size: 0.5mg, 1mg, 200µg
- Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Histone-lysine N-methyltransferase, H3 lysine-79 specific, EC 2.1.1.43, Histone H3-K79 methyltransferase, dot1
For Research Use Only | Not For Clinical Use.
