MHC class II antigen
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants.
Mouse Anti-DPM1 Antibody (CBMOAB-01070CR) (CAT#: CBMOAB-01070CR)
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- Host species: Mouse
- Species Reactivity: Yeast, C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Hamsters (Cricetinae), Mallard (Anas platyrhynchos), Pig (Sus scrofa), Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
- Application: WB, ELISA
- Protein: Dolichol-phosphate mannosyltransferase
- Size: 0.5mg, 1mg, 200µg
- Conjugate: AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Dolichol-phosphate mannosyltransferase, EC 2.4.1.83, Dolichol-phosphate mannose synthase, DPM synthase, Dolichyl-phosphate beta-D-mannosyltransferase, Mannose-P-dolichol synthase, MPD synthase, DPM1, SED3, YPR183W
For Research Use Only | Not For Clinical Use.
