Quinidine
Quinidine is a class I antiarrhythmic drug. Like all other class I antiarrhythmic drugs, quinidine acts primarily by blocking the fast inward sodium current (INa), which results in decreased phase 0 depolarization (decreased Vmax) of the cardiac action potential. Quinidine also blocks the slowly inactivated, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the fast (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI) , ATP-sensitive potassium channel (IKATP) and Ito. At micromolar concentrations, quinidine inhibits Na/K-ATPase by binding to the same receptor site as digitonin such as ouabain.
Mouse Anti-Quinidine Antibody (MOFAB-084W) (CAT#: MOFAB-084W)
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- Host species: Mouse
- Application: ELISA
- Protein: Quinidine resistance protein 1
- Size: 0.5mg, 100µg
- Conjugate: None
- Alternative Names: Quinidine, AB675_7106, Quinidine resistance protein 1, Quinidine
For Research Use Only | Not For Clinical Use.