Zinc/RING finger protein 3 isoform 1
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Mouse Anti-znrf3 Antibody (CBMOAB-18232FYB) (CAT#: CBMOAB-18232FYB)
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- Host species: Mouse
- Species Reactivity: Zebrafish (Danio rerio), Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: E3 ubiquitin-protein ligase znrf3
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: E3 ubiquitin-protein ligase ZNRF3, EC 6.3.2.-, Zinc/RING finger protein 3, znrf
For Research Use Only | Not For Clinical Use.
