Mouse Anti-ADAM17 Antibody (CBMOAB-35094FYA)

Cat: CBMOAB-35094FYA

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Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-35094FYA	Monoclonal	Rhesus (Macaca mulatta), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Frog (Xenopus laevis), Marmoset, Pig (Sus scrofa)	WB, ELISA	MO35094FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 813 amino acids long. The sequence is show below: MRQSLLFLTSVVPFVLAPRPPDDPSFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDRGPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQR.
MO-AB-00046Y	Monoclonal	Chicken (Gallus gallus)	WB, ELISA	MO00046Y		100 µg	Inquiry
Protein Refseq: The length of the protein is 829 amino acids long. The sequence is show below: MRLRLWLVSALALLWAPGGLQALGRLPREQRYDAVESMLSNYDILSQSSIQQHSLKKRDLQPETHVERLLSFSALQRHFKLYLTATAEHFSERFQALIVDGEGKEKEYRVQWQDFFTGHVVGEHNSKVVAHIGDEDFTVRINTDGEEYNIEPLWRFIDNVQDERLLVYRSEDIKDFSRLQSPKVCGYLKLNEDELLPKGLEESKQNEASIHREKRAIPESSKDTCKMLVVADHRFFKYMGRGEESTTINYLIELIDRVDDIYRNTSWDNEAFKGYGIQIEQIIIHSEPERVAPGGKHYNMAKSYPDDKKDAWDVKMLLEQFSFDIAEKAAHVCLAHLFTYQDFDMGTLGLAYVGSPRPNSHGGICPKAYHSPIVKKDIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDSLPECAPTEDQGGKYVMYPIAVSGDHENNKMFSSCSKKSIHRTIEVKAQECFKERNNKVCGNSRVDEGEECDPGLLYQRVDPCCSADCKLKDGAKCSDRNSPCCKGCQFESAQKKCQEAINATCKGESFCTGNSSECPPPGNAPDDTICVDMGKCKDGECIPFCEREKNLRSCACNETDNSCKVCCRDEQDRCTPYVDANNQFLFLRKGKPCTVGFCDSNGKCEKQVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLLFWIPLSILVHCVDKKLDKQYEENNKSLFCASNAEVPSSLDSASVRIIKPFPAAQPTSRHQPLQPIVAAPAAATAPKQDHQRMDTIQEDPSTDSHIDEDGFEKDPFPNSSSAAKSFEDLTEHPVTRSEKASSFKLQRQNRVDSKETEC.
MO-AB-01228H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO01228C		100 µg	Inquiry
Protein Refseq: The length of the protein is 839 amino acids long. The sequence is show below: MKTLRPLGRLSLVEVVLVLLLCLAGAEAEHIPYGNQKEMPAKHQGLDSMLSEYDVLSLSSIQQHSLRKRDLQTQSQVERMLSFTALQRHFKLYLASSTELFSENLQALVLDGNGKEEKYQVKWSDFFTGHVVGEHNSKVLAHIGDGDFTARITTDGDEYNIEPLWRFVENTSRDNMLVYRSEDVKDFSRLKSSKVCGYVKPKEDLFKNEQDTAEAPEGNDYLHREKRQRAVPDPMKNTCKMVVVADHRFFKYMGRGEESTTINYLIELIDRVDDIYKNTSWDSQWKGYGVQIEQIIVHKEPENVTQGQKHYNMAKSFPNPDKDAWDVKQLLEQFSFDISDKAAQVCLAHLFTYQDFDMGTLGLAYVGSHKPNTHGGICPKAYENDLSKKAVYLNTGLTSTKNYGKTILTKEADLVTTHELGHNFGSEHDPDSMEACAPSEDRGGKFVMYPIAVSGDHENNKMFSNCSREAILRTLMAKSPICFKERNNKVCGNSRVDEGEECDPGLLHQHNDDCCTSDCKFKPGVLCSDRNSPCCKGCQFETAQKKCQEAINATCKGESYCTGSSSECPTPGNAENDTVCVDLGKCVNGECRPFCEIELNLKSCACNDTENSCKVCCRNENGICSPYVDKNKQFLYLRKGKPCTVGFCDMNGKCEKQVQDVIERIWDFIDKLSINMFGKFLADNIVGSVVVFSLIFWIPLSILVHCVDKKLDKRYEETTKSLFTPSNVEMLSSMDSAPVRIVKPPPSSQATSRFQVVPIVPTSAAASTKADHQRMDTIQEDPSVDSHLDDQFEEAPFPNSGSPAKSFEDLTDRPVVRSEKASSFRLQRQGRVDSKETEC.
MO-AB-22852W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO22852W		100 µg	Inquiry
Protein Refseq: The length of the protein is 824 amino acids long. The sequence is show below: MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEDVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC.
MO-AB-23524R	Monoclonal	Pig (Sus scrofa)	WB, ELISA	MO23524R		100 µg	Inquiry
Protein Refseq: The length of the protein is 833 amino acids long. The sequence is show below: MRQCALFLTSLVPIVLAPRPPDEPGFGSPQRLEKLDSLLSDYDILSLSSIRQHSVRKRDLQASTHLETLLTFSALNRHFKLYLTSSTERFSQNFKVVVVDGEDESEYPVKWQDFFSGHVVGEPDSRVLAHIGDDDITVRINTDGAEYNIEPLWRLINDTKDKRVLVYKSEDIKNVSRLQSPKVCGYIKADNEELLPKGLVDREPPDELVHRVKRRADPNPLRNTCKLLVVADHRFYKYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGERHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLRPGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGRCKDGKCVPFCEREQRLESCACNETDHSCKVCCRAPSGRCLPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWEFIDKLSINTFGKFLADNIVGSVLVFSLMLWIPVSILVHCVDKKLDKQYESLSLLHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPLQPLQPGPVLPSAPSVPVAPKLDHQRMDTIQEDPSTDSHVDEDGFEKDPFPNSSAAAKSFEDLTDHPVTRSEKASSFKLQRQSRVDSKETEC.
MO-AB-28817W	Monoclonal	Dog (Canis lupus familiaris)	WB, ELISA	MO28817W		100 µg	Inquiry
Protein Refseq: The length of the protein is 823 amino acids long. The sequence is show below: MRRCVLFWTSVVPLVLAPRPPEQPPQRLENLDSLPSDYDILSLSNIQQHSVRKRDLQASTHIETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKDESEYTVKWQDFFSGHVVGEPDSRVLAHIGDDDMTIRINTDGAEYNIEPLWRLINDTKDKRMLVYKSEDIKNVSRLQSPKVCGYIKADNEELLPKGLVDREPPDEFVHRVKRRADPNPLKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGERHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKSQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCSSDCMLRAGVQCSDRNSPCCKNSQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAADDIVCLDLGKCKDGKCVPFCEREQHLESCACNETDNSCKVCCRDPSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRPQPLQAAPVPPPMPAAPKLEHQRMDTIQEDPSTDSHVDEDGFEKDPFPNSSTAAKSFEDLTGRPVTRSEKAASFKLQRQNRVGSKETEC.
MO-AB-50436W	Monoclonal	Marmoset	WB, ELISA	MO50436W		100 µg	Inquiry
Protein Refseq: The length of the protein is 824 amino acids long. The sequence is show below: MRQSLLFLTSVVPLVLAPRPPEDPAFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHAETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYAVKWQDFFTGHVVGEPDSKVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLIDREPPEELVHRVKRRAVPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPTGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMFPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNSDTCCNSDCMLKQGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQRNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Rhesus (Macaca mulatta), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Frog (Xenopus laevis), Marmoset, Pig (Sus scrofa)
Clone	MO35094FYA
Specificity	This antibody binds to Rhesus ADAM17.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor. This protease also functions in the processing of numerous other substrates, including cell adhesion proteins, cytokine and growth factor receptors and epidermal growth factor (EGF) receptor ligands. The encoded protein also plays a prominent role in the activation of the Notch signaling pathway. Elevated expression of this gene has been observed in specific cell types derived from psoriasis, rheumatoid arthritis, multiple sclerosis and Crohn's disease patients, suggesting that the encoded protein may play a role in autoimmune disease.
Product Overview	Mouse Anti-Rhesus ADAM17 Antibody is a mouse antibody against ADAM17. It can be used for ADAM17 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Disintegrin and metalloproteinase domain-containing protein 17 preproprotein; ADAM17
UniProt ID	H9F0T0
Protein Refseq	The length of the protein is 813 amino acids long. The sequence is show below: MRQSLLFLTSVVPFVLAPRPPDDPSFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDRGPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQR.

For Research Use Only | Not For Clinical Use.

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