Mouse Anti-ADD2 Antibody (CBMOAB-00377HCB)

Cat: CBMOAB-00377HCB

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Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-00377HCB	Monoclonal	C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rhesus (Macaca mulatta), Marmoset, Zebrafish (Danio rerio)	WB, ELISA	MO00377HB		100 µg	Inquiry
Protein Refseq: The length of the protein is 611 amino acids long. The sequence is show below: MSDGSDDDTNNDGNYCKNVSYNFLIQRLAEVSNRKCLLLPKKKNRVDYISIMQTAEFYPELVNSSPPLEPGFTSCEVFVVDKKVDKDTLHLDNFSPYHIGATRRTLERQHSYFYRVNESGNFVPAIKTNGTHILRILVSILGSCPALNRKIYRMVKIESQNKNCLPSLIVYTFEPGHEIPKPNAPAILRRQTSDEIQKILNIPGTSFSQAHSEAVLNRFYDDLPIRDEASDQKRARYSIESTSSTNNQLNEINSFVVPKFEGRQESEQLFRDVKVEQFEESAEISINNRALSPHIQPSKTSVVNRPNQQNRKFQNYDMFSAGVISTATVPAPMFHPHITPIADLKDDDGYDPEELTQRNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMIVGDVGYHEYRGILIDEAERALLVRDLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTGNVPN.
CBMOAB-35214FYA	Monoclonal	Rhesus (Macaca mulatta)	WB, ELISA	MO35214FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 587 amino acids long. The sequence is show below: MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNQAADLRQDFNLMEQKKRVTMILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDEDTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDAPGWFSS.
CBMOAB-64995FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO64995FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 670 amino acids long. The sequence is show below: RVICVFQSFREELDVLIQEQMKKGGSSSNLWALRQIADFMATHGSPAALPVTPSTVTIVTPINDLHGWEPSSMVKGERLMRCKLASVHRLLDLYGWAQLANTCLTMRVSKEQEHFLVLPDGLAYGEVTASSLVKVNILGEVVEKGSTALAVDLSSFSLHSAIYSARPDVRCLLHLHTPATAAVSAMKCGLLPLSHEALLVGEVAYYDYNGVMEEEEDRVELQKSLGPTCKVLVLRNHGIVALGESVEEAFYTIYHIQTACQIQVVAALCSAGGEQNLIMLDRNVHRPVAKGTVGWAGSTFGPMQKSRLGEHEFEALMRTLDNLGYRTGYAYRFPVLLERSRTRREVEVPATVTSFSFHEDGVQPHPRLHPHTQRQQQKTRWLNTPNVYQKVNQDQASPGHRTTWQKSEEITQGSGRAIKIENPNQFVPLFTNPKEVLETRNKIREQNRQDMKTAGPQSQVLASVITDNSPPVRSQSVFQSPEIVEPPVPPEPETPNPFNELTDHELEEYRKEVQRKQHGQQDGVEEVVNDTGSSPTTSPIKTPAASDKLPFTDNLRAQNRSVLKDSSNIVKPSQSPAPPPTPHEKTADAVQNDKGDEKKKQEELEKQMKALSTTDTSETTLSAPPTAPPNKPAGNTPEGSPSKSPSKKKKKFKAPCFLKKSKKQKEKAET.
MO-AB-07026R	Monoclonal	Cattle (Bos taurus)	WB, ELISA	MO07026R		100 µg	Inquiry
Protein Refseq: The length of the protein is 724 amino acids long. The sequence is show below: MSEETVPEAASPPPAQGQQYFDRFSEDDPEYLRLRSRAADLRQDFNLMEQKKRVTMILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNFSMMTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHDALLVGD.
MO-AB-23976H	Monoclonal	Rat (Rattus norvegicus)	WB, ELISA	MO23976C		100 µg	Inquiry
Protein Refseq: The length of the protein is 39 amino acids long. The sequence is show below: KEVERKKLEQEQEGRSRGKPELWRACSSPARREKDAATE.
MO-AB-50487W	Monoclonal	Marmoset	WB, ELISA	MO50487W		100 µg	Inquiry
Protein Refseq: The length of the protein is 726 amino acids long. The sequence is show below: MSEETVPEAASPPPPQGQPYFDRFSEDDPEYMRLRNRAADLRQDFNLMEQKKRVTMILQSPSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNVSMMTPINDLHTADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEVTASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMKWGLLPVSHNALLVGDMAYYDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVEEAFYKIFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALRQHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSKGDADTKDDSEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKETAPEEPGSPAKSAPPSPVQSPVKEAETKSPVVSPSKSLEEGAKKTETSKDTTTEPETTQPEGVVVNGREEEQTAEEILSKGLSQMTTSADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKEKVES.
MO-DKB-01521W	Polyclonal	Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rhesus (Macaca mulatta)	WB			100 µg	Inquiry

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), Rhesus (Macaca mulatta), Marmoset, Zebrafish (Danio rerio)
Clone	MO00377HB
Specificity	This antibody binds to C. elegans ADD2.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Plasma Membrane; Cytoskeleton; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced transcript variants have been described.
Product Overview	Mouse Anti-C. elegans ADD2 Antibody is a mouse antibody against ADD2. It can be used for ADD2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Adducin-related protein 2; add-2
Gene ID	179647
UniProt ID	Q20952
Protein Refseq	The length of the protein is 611 amino acids long. The sequence is show below: MSDGSDDDTNNDGNYCKNVSYNFLIQRLAEVSNRKCLLLPKKKNRVDYISIMQTAEFYPELVNSSPPLEPGFTSCEVFVVDKKVDKDTLHLDNFSPYHIGATRRTLERQHSYFYRVNESGNFVPAIKTNGTHILRILVSILGSCPALNRKIYRMVKIESQNKNCLPSLIVYTFEPGHEIPKPNAPAILRRQTSDEIQKILNIPGTSFSQAHSEAVLNRFYDDLPIRDEASDQKRARYSIESTSSTNNQLNEINSFVVPKFEGRQESEQLFRDVKVEQFEESAEISINNRALSPHIQPSKTSVVNRPNQQNRKFQNYDMFSAGVISTATVPAPMFHPHITPIADLKDDDGYDPEELTQRNKLASLYRLVDLFRWSQGIYNHITVRVSTDPDEILINAFGQLYSEVSASSLIKVDLDGTVIDGGSTNFGVNQAGYVLHSAIHNGRPEVKCVVHLHHPSVVAVSAQKCGLLPISQESMIVGDVGYHEYRGILIDEAERALLVRDLGDRNVMILRNHGFVVCGESIEHALSLTYHLIIACETQIRTVPGGNTDNVHFPAQSAIKQVYKVASQGGGGVNRQNGHVNSMQWKKGELEWQAYMRQLDAQGYVTGNVPN.

For Research Use Only | Not For Clinical Use.

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