Mouse Anti-ADRA2C Antibody (CBMOAB-35264FYA)


Cat: CBMOAB-35264FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-35264FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Guinea pig (Cavia porcellus), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, ELISA MO35264FYA 100 µg
CBMOAB-65093FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO65093FYA 100 µg
MO-AB-07080R Monoclonal Cattle (Bos taurus) WB, ELISA MO07080R 100 µg
MO-AB-14105Y Monoclonal Sheep (Ovis aries) WB, ELISA MO14105Y 100 µg
MO-AB-41187W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO41187W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Guinea pig (Cavia porcellus), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMO35264FYA
SpecificityThis antibody binds to Rhesus ADRA2C.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionAlpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
Product OverviewMouse Anti-Rhesus ADRA2C Antibody is a mouse antibody against ADRA2C. It can be used for ADRA2C detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesADRA2C
UniProt IDF7GMM7
Protein RefseqThe length of the protein is 407 amino acids long.
The sequence is show below: MASPALAAALAVAAAAGPNASGAGERGSGANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPRADVEPDESSEAAERRRRRGALRRGRRRRAGAEGGAGGADGQGAAESGALTRESRAPGSGEERGGDPFAFPPQQGAASGAPCLDPAVGALPRCGCEVRVLESSVRGSFLNGRARSPPKHTTTPHPRLTKG.
For Research Use Only | Not For Clinical Use.
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