AibGenesis™ Mouse Anti-AIFM1 Antibody (CBMOAB-35377FYA)


Cat: CBMOAB-35377FYA

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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-35377FYA Monoclonal Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Cow, Human, Mouse, Rat, Marmoset, Pig (Sus scrofa), Zebrafish (Danio rerio) WB, ELISA MO35377FYA 100 µg
CBMOAB-65316FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO65316FYA 100 µg
MO-AB-17245W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO17245W 100 µg
MO-AB-23650R Monoclonal Pig (Sus scrofa) WB, ELISA MO23650R 100 µg
MO-AB-50622W Monoclonal Marmoset WB, ELISA MO50622W 100 µg
MOFAB-764W Monoclonal Cow, Human, Mouse, Rat WB, IP 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Cow, Human, Mouse, Rat, Marmoset, Pig (Sus scrofa), Zebrafish (Danio rerio)
CloneMO35377FYA
SpecificityThis antibody binds to Rhesus AIFM1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6), a severe mitochondrial encephalomyopathy, as well as Cowchock syndrome, also known as X-linked recessive Charcot-Marie-Tooth disease-4 (CMTX-4), a disorder resulting in neuropathy, and axonal and motor-sensory defects with deafness and cognitive disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. (From NCBI)
Product OverviewMouse Anti-Rhesus AIFM1 Antibody is a mouse antibody against AIFM1. It can be used for AIFM1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAIFM1
UniProt IDF7C728
Protein RefseqThe length of the protein is 326 amino acids long.
The sequence is show below: MFRCGGLAAGALKQKLVPLVRTVCVRSPRQRNRLPARALGTEVIQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLIKLKDGRKVETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQARSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQSMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPRSATEQSGTGIRSESETESEASEIAIPPSTPAVPQAPVQGEDYGKGVIFYLRDKVVVGIVLWNIFNRMPIARKIIKDGEQHEDLNEVAKLFNIHED.
For Research Use Only | Not For Clinical Use.
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