Mouse Anti-AIPL1 Antibody (CBMOAB-00451HCB)
Cat: CBMOAB-00451HCB
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-00451HCB | Monoclonal | C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Rhesus (Macaca mulatta) | WB, ELISA | MO00451HB | 100 µg | ||
CBMOAB-35396FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO35396FYA | 100 µg | ||
MO-AB-07171R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO07171R | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Rhesus (Macaca mulatta) |
Clone | MO00451HB |
Specificity | This antibody binds to C. elegans AIPL1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Cytoskeleton |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants. |
Product Overview | Mouse Anti-C. elegans AIPL1 Antibody is a mouse antibody against AIPL1. It can be used for AIPL1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Protein AIPL-1; aipl-1 |
Gene ID | 179898 |
UniProt ID | O17939 |
Protein Refseq | The length of the protein is 600 amino acids long. The sequence is show below: MSEFSQTAVFPSLPRAARGVPVILGSSPAGDKILYCNGNSVFTIPIDSLNSADIYTEHAHQTTVAKISPTGFYCASGDTQGNIRIWDTTQSTHILKHTIPVFSGPVKDIAWDSESKRIAAVGEGKERFGHVFLLDTTTSNGSLTGQSRTMNSVDFKPTRPFRIISGSDDNTVAIFEGPPFKFKHTFDHHKKFVQSTRYNNDGSLFASTGSDGTVVLYNGVDGEKVGVLEDAKGVAHTGSIFALAWSPDQSRIATASADKSVKIWDVSARKLERTIVMGSKIEDQQLGIVWTKSALITVSVSGFLNFLNPDDGSVEKIRQGHNKAITALSKSSDGKFLFSADAEGHITTWEISSGTSSRKSPHTTMITGAQTSSNGDLFTVGWDDQLKITDGSGDTKSFKLPSQPCGLEVSDDLAIVACYKHVVVLSRGTPTENPIEFHSTCVAFCAEKSLVAVGGKDAKVHVYKLNGDGRLEELKKIEHSAEITAVSFSDDGEYLAVTDLARKVIPYSVSTDFSVTSPNSWTFHTSKVLTVAWSPDNQRLATGSIDTSVIIWDMKKPGEHPVIIKGAHPMSSVNVVRWLDETTVVSAGQDSNIKFWNVPL. |
For Research Use Only | Not For Clinical Use.
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