Mouse Anti-AIPL1 Antibody (CBMOAB-00451HCB)


Cat: CBMOAB-00451HCB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-00451HCB Monoclonal C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Rhesus (Macaca mulatta) WB, ELISA MO00451HB 100 µg
CBMOAB-35396FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO35396FYA 100 µg
MO-AB-07171R Monoclonal Cattle (Bos taurus) WB, ELISA MO07171R 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Rhesus (Macaca mulatta)
CloneMO00451HB
SpecificityThis antibody binds to C. elegans AIPL1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationCytoskeleton

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionLeber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants.
Product OverviewMouse Anti-C. elegans AIPL1 Antibody is a mouse antibody against AIPL1. It can be used for AIPL1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein AIPL-1; aipl-1
Gene ID179898
UniProt IDO17939
Protein RefseqThe length of the protein is 600 amino acids long. The sequence is show below: MSEFSQTAVFPSLPRAARGVPVILGSSPAGDKILYCNGNSVFTIPIDSLNSADIYTEHAHQTTVAKISPTGFYCASGDTQGNIRIWDTTQSTHILKHTIPVFSGPVKDIAWDSESKRIAAVGEGKERFGHVFLLDTTTSNGSLTGQSRTMNSVDFKPTRPFRIISGSDDNTVAIFEGPPFKFKHTFDHHKKFVQSTRYNNDGSLFASTGSDGTVVLYNGVDGEKVGVLEDAKGVAHTGSIFALAWSPDQSRIATASADKSVKIWDVSARKLERTIVMGSKIEDQQLGIVWTKSALITVSVSGFLNFLNPDDGSVEKIRQGHNKAITALSKSSDGKFLFSADAEGHITTWEISSGTSSRKSPHTTMITGAQTSSNGDLFTVGWDDQLKITDGSGDTKSFKLPSQPCGLEVSDDLAIVACYKHVVVLSRGTPTENPIEFHSTCVAFCAEKSLVAVGGKDAKVHVYKLNGDGRLEELKKIEHSAEITAVSFSDDGEYLAVTDLARKVIPYSVSTDFSVTSPNSWTFHTSKVLTVAWSPDNQRLATGSIDTSVIIWDMKKPGEHPVIIKGAHPMSSVNVVRWLDETTVVSAGQDSNIKFWNVPL.
For Research Use Only | Not For Clinical Use.
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