Mouse Anti-ALKBH8 Antibody (CBMOAB-35539FYA)

Cat: CBMOAB-35539FYA

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-35539FYA	Monoclonal	Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio)	WB, ELISA	MO35539FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 243 amino acids long. The sequence is show below: YGIPFLLQVGCDRSQNLVDICRERQFQAFVCDALAVPVCSGSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLKGNRNSQGKKEEMNSDTSVQRSLVEQMPDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPIHVNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEALCRTVSDVRILQSYYDQGNWCVILQKA.
CBMOAB-65573FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO65573FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 666 amino acids long. The sequence is show below: MESSRSVRRTKEEKKLLRRQIKASHTLLKHEDITTVSHPTKHLVVSNGGLGNGVSRESLLEVLKEGGTVESLLTPPSKPYAFVSYSSIEAGQNAYTLLNGRTLQCQDQTMTLYFSYVVKVDCDRSVSCALPPGLSVLEDFVSLEEELQILKAVDWTPHADDVTAQKALKHRRVKHYGYEFRYDNNNVDKDKPLPGGLPVECDALLQRCLAGGHISVLPDQLTVNQYQSGQGIPPHVDTHSPFEDTILSLSLGAKTVMDFKHPDGRSVAVVLPERSLLVMKGESRYLWTHGITPRKFDVVPVSETGGSGVMTSDLSNLTLSRRDTRTSLTFRKIRHTPCNCAYPSVCDSQRPPSPPVVPVAEGDACRLESQYVHQVYEEISSHFSSTRHSPWPKVRDFLLSLPPGSFLADVGCGNGKYLGINPAVRAVGCDRSVNLVQICIERGYDAFVSDALSVPLRRGSCDACISIAVIHHFATQERRRAAVRELIRLIKVGGRALIYVWAMEQEYNNQKSKYLKEEASGSSREGGEELKTEENKAIQKEEHDRNMISDIRCTDDGLSNVTQPKIHVHTNRTAFLSQDLLVPWHLKGNMENKKGAASGCADIPVENAKQKPVFHRYYHVFQQGELEELCLGVKGVKVLRSYHDQGNWCVELEKTHGNFSIIAAGK.
MO-AB-07264R	Monoclonal	Cattle (Bos taurus)	WB, ELISA	MO07264R		100 µg	Inquiry
Protein Refseq: The length of the protein is 664 amino acids long. The sequence is show below: MDSNHQSNYKLSKTEKKLLRKQIKARHTLLRHEGIETVSYATQSLIVANGGLGNQVSRNQLLPVLEKCGLVDALLMPPNKPYSCVRYKTVEESKTAYDTLNGKEIVDDLGQKIILYLNFVEKAQWKELGLQALPPGLKVIEEIISSEDEKMLLESVNWTEDTENQNFQKSLKHRRVKHFGYEFHYENNNVDKDKPLPGGLPDICESILEKWLKEGFIKHKPDQLTINQYEPGHGIPAHIDTHSAFEDEIISLSLG.
MO-AB-15363W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO15363W		100 µg	Inquiry
Protein Refseq: The length of the protein is 664 amino acids long. The sequence is show below: MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQLLPVLEKCGLVDALLMPPNKPYSFARYKTTEESKRAYVTLNGKEVVDDLGQKIILYLNFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICDSFLEKWLREGYIKHKPDQMTINQYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKYLGINKELYMIGGDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSVQRSLVEQMPDMGSQDSPFSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEAACRTVSDVRILQSYYDQGNWCVILQKA.
MO-AB-50749W	Monoclonal	Marmoset	WB, ELISA	MO50749W		100 µg	Inquiry
Protein Refseq: The length of the protein is 661 amino acids long. The sequence is show below: MDSSHHGNYKLSKAEKKFLRKQIKASHTLLRHEGIQTVSCATQSLVVANGGLGNGMCRNQLLPVLEKCGLVDALLMPPNKPYSFARYKTVEESKRAYVTLNGKEVVDDLGHKIILYLNFVEKAQWKELRPPALPPGLVVVEEIISSEDEKMLLESVDWTKDTDNQNSQKSLKHRRVKHFGYEFHYEGNNVDKDKPLSGGLPDICDSFLEKWLREGYIKHKPDQMTINQYEPGHGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGITVPVMLPRRSLLVMTGESRYLWTHGITCRKFDTVQASGSQKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRRETPPSFPESDKEASRLEQEHVHQVYEEIAGHFSSTRHTPWPHVVEFLKALPNGSVVADIGCGNGKYLGVNKELYTIGCDRSQNLVDICRERQFQALVCDALAVPVRSGVCDACISIAVIHHFATAERRVAAVQELVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRTSQEKKEEMNGDTSVQRLLVEQMSDLGSRDSASSVPCIREGRGNSRQVSDSKLPIHVNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGPHDPSPVFHRYYHVFREGELEAACRTVSDVRVLQSYYDQGNWCVILQKA.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio)
Clone	MO35539FYA
Specificity	This antibody binds to Rhesus ALKBH8.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine; has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182).
Product Overview	Mouse Anti-Rhesus ALKBH8 Antibody is a mouse antibody against ALKBH8. It can be used for ALKBH8 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	ALKBH8
UniProt ID	F7GQ66
Protein Refseq	The length of the protein is 243 amino acids long. The sequence is show below: YGIPFLLQVGCDRSQNLVDICRERQFQAFVCDALAVPVCSGSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLKGNRNSQGKKEEMNSDTSVQRSLVEQMPDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPIHVNRTSFYSQDVLVPWHLKGNPDKGKPVEPFGPIGSQDPSPVFHRYYHVFREGELEALCRTVSDVRILQSYYDQGNWCVILQKA.

For Research Use Only | Not For Clinical Use.

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