Mouse Anti-APC4 Antibody (CBMOAB-00247CR)

Cat: CBMOAB-00247CR

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-00247CR	Monoclonal	Yeast, A. thaliana (Arabidopsis thaliana), Fruit fly (Drosophila melanogaster)	WB, ELISA	MO00247CR		100 µg	Inquiry
Protein Refseq: The length of the protein is 652 amino acids long. The sequence is show below: MSSPINDYFIDYNPLFPIFATRIAKGLAIYRVSDHARLAVIPIRNINLVANYDWDTTTGKFLSIFFKDGTIRIHDIFKDGRLVSFLRIPSTKISKGIWDRIPLRYEPNNRDFACNIIDDLPKLIRFVKDSKRINIVPYTQPNSLWRGPDEDDLDSNEKLDVHVVFNEGNDKITVFFNGDYAVFLSVDNIENENSLKSIIKVQDGFYQCFYEDGTVQTLNLGPLLQSKSSVNLLNYIMVIKELIGYMLTHLEFINRELATPYLDFVKRLCDEAYGYGKLKSELEALFLLGEISCDLEDWLCNSVGEKNFKRWKYLGCEAYQKTVQILTLIFVPACERIIIYVEKLRAILQAFSIQNKLSYTSDLTAVEVLLKSSQKLLTMTLNSIIGLGRDETLFEKFFIWFNDRLHEALDEDYKLKFQFEDDLYFGYDLLSYFDRILSKKGTEPSSIIDVKLYRDLINSMSDMEKDIAQSNVNSHIQQHILVDLKTDVFAQKYPSSQINLLDAIKLPKHNYIVYLIQVTKHNSAQEPFSEENKKKLYIGTLKDENLGIISKESSVKIPALFKSYRLSSTRFVPNRVHSLLRDIGLSDSNYHSSHVTDYRGENYENEEDDGTIAIPAYIRENRENDDFIACTAKVSVDGRSASLVFPKEKQNV.
CBMOAB-01097FYA	Monoclonal	Fruit fly (Drosophila melanogaster)	WB, ELISA	MO01097FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 773 amino acids long. The sequence is show below: MAQTSSMKLLGARNMSCIVERMEWNNKMDLIAYGTEKGEVVIQRLNWQKIVTFPTPGEDVRVRSLSWQMDETLLAVGYSNGKVALLDAESGTIISGLIYEDDIKKVYFSKAINSQENLGTYTCNVKDKHRRFLPKLQPMTNIDPCLKTLDQKSFPKGSPCFLVVIMRSGKVHLLLLGALQAGSIDLTQHILHPHEFDVYDVRMNGDCNAIYALLRDGQELILLHFQNQVLQDCMAPMLELATHCAHILETKNYINDTQQCLTEAWETVQLEMDNKLTRYANSQPYGVISAHFLELHVFGFATFEVEEFLTLSEKGFKKIANSVDLSLSNLQSLVFKQLNGAAINMFYFLNTIAGFGRMSHFFESLISPDVANEAMRACGGFVLKVHELQRTIDTLAYDMKLFHAWMIFTILRLSHQEIPDDLVLTEEENIAMADFICAMEPELDDRSDDEDELDSQSQTPPPARSKFNLERVGQYLDNAYLTQLYPRDPVQLWEEMVTDNECLSNCKLFVPHDVNLSLVQQRDKMFNAIDAVFHKPTESISGSFKVSSTVICNDLPPMEPGEDHRDRDLVTCTYYVNEASRTDMLACTISGQEAMILEFSRAGDECVRCTRITLEPGLFTTSVSEDFCYLRFVDLQFYNESSLSILAQSINAGPGMRPHSFFIQFSLTAALNYSTQHRMGPLVKLSEATVSQSIHDIADGAAFKGLDGFSDMLAVSGSRKVATVLSDRKRKMTIFEMEIEEEEDDTEMSQASFLDISKESVLAGVPDAEKQEA.
CBMOAB-2257FYC	Monoclonal	A. thaliana (Arabidopsis thaliana)	WB, ELISA	MO2257FC		100 µg	Inquiry
Protein Refseq: The length of the protein is 777 amino acids long. The sequence is show below: MSEMASDEEENIIPFQLQFDKPIPFQIKIAEWNPEKDLLAMVTEDSKILLHRFNWQRLWTISPGKPVTSLCWRPDGKAIAVGLEDGTISLHDVENGKLLRNLKPHDVAVVCLNWEEDGQSNTDESGNFSVYEDRTSRFFPPAPRPPKMPGLVAGDSSFMDDGEDSLAELSNTSFRKFNILCTGDRDGNICFSIFGIFQIGKINIHELSLPVPHLDEHASCKLFNASIYKVALSKDLCRLVVMCTGELKDCDIKPREEKINVQDLPGLHCLAMDTSIFWKRKYELHQVAQQASNIEDLTEVIRASLSVMNKQWADAMKTFHEKFHSLSTLIIDNGLESSPQEEFLSLLGGARISPALNQFLVNSLGEVGVKRVLKSVCGTGKELQQVVLDHLQPAAEIIGFRIGELRGLSRWRARYQGIGLDEMLLNEATENTGLLLVQVQRFMMVLSSVVQQFSNFFNWLVRSIKYLMQEPNDQLLSYNSELLVVFLKFLYDQDPVKDLLELSEAGDDIEIDLKTIGRVKELLQFGGFSECDFLQRTLAKEFQHMESSFKMAFQMPFTTISRKISCMKLLPLCPLQLSTTQTPTTIPMSLSFYKNELSDDTPCQSGYTDYISFQVPDETFPEISNCIGIAKGYKQNSNNEKNGYTSLEAVLLSVPNGYTCVDLSLYKDKELVLLLNKTNTDSEGSGEACMMVVQTGDLAFISISGSSSLNQWELEDLKGSIVNLEMENEKVRKVPHSVIAPLAVSASRGVACVFAERRRALVYILEEDEDEEISDEK.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Yeast, A. thaliana (Arabidopsis thaliana), Fruit fly (Drosophila melanogaster)
Clone	MO00247CR
Specificity	This antibody binds to Yeast APC4.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition. In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.
Product Overview	Mouse Anti-Yeast APC4 Antibody is a mouse antibody against APC4. It can be used for APC4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Anaphase-promoting complex subunit 4; APC4; YDR118W
UniProt ID	Q04601
Protein Refseq	The length of the protein is 652 amino acids long. The sequence is show below: MSSPINDYFIDYNPLFPIFATRIAKGLAIYRVSDHARLAVIPIRNINLVANYDWDTTTGKFLSIFFKDGTIRIHDIFKDGRLVSFLRIPSTKISKGIWDRIPLRYEPNNRDFACNIIDDLPKLIRFVKDSKRINIVPYTQPNSLWRGPDEDDLDSNEKLDVHVVFNEGNDKITVFFNGDYAVFLSVDNIENENSLKSIIKVQDGFYQCFYEDGTVQTLNLGPLLQSKSSVNLLNYIMVIKELIGYMLTHLEFINRELATPYLDFVKRLCDEAYGYGKLKSELEALFLLGEISCDLEDWLCNSVGEKNFKRWKYLGCEAYQKTVQILTLIFVPACERIIIYVEKLRAILQAFSIQNKLSYTSDLTAVEVLLKSSQKLLTMTLNSIIGLGRDETLFEKFFIWFNDRLHEALDEDYKLKFQFEDDLYFGYDLLSYFDRILSKKGTEPSSIIDVKLYRDLINSMSDMEKDIAQSNVNSHIQQHILVDLKTDVFAQKYPSSQINLLDAIKLPKHNYIVYLIQVTKHNSAQEPFSEENKKKLYIGTLKDENLGIISKESSVKIPALFKSYRLSSTRFVPNRVHSLLRDIGLSDSNYHSSHVTDYRGENYENEEDDGTIAIPAYIRENRENDDFIACTAKVSVDGRSASLVFPKEKQNV.

For Research Use Only | Not For Clinical Use.

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