Mouse Anti-Arabidopsis ABCG8 Antibody (CBMOAB-1356FYC)


Cat: CBMOAB-1356FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO1356FC
SpecificityThis antibody binds to Arabidopsis ABCG8.
FormatLyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.
Product OverviewMouse Anti-Arabidopsis ABCG8 (clone MO1356FC) Antibody (CBMOAB-1356FYC) is a mouse antibody against ABCG8. It can be used for ABCG8 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesATP Binding Cassette Subfamily G Member 8; ATP-Binding Cassette, Sub-Family G (WHITE), Member 8; Sterolin 2; ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (Sterolin 2); ATP-Binding Cassette Sub-Family G Member 8; Gallbladder Disease 4; Sterolin-2; STSL; GBD4
UniProt IDQ9FLX5
Protein RefseqThe length of the protein is 589 amino acids long. The sequence is show below: MEIPPSPPPETAAYTLTTSSISYTIPKTSLSLLRFPATEPPSFILRNITLTAHPTEILAVVGPSGAGKSTLLDILASKTSPTSGSILLNSIPINPSSYRKISSYVPQHDSFFPLLTVSETFSFAACLLLPNPSIVSETVTSLLSELNLTHLSHTRLAQGLSGGERRRVSIGLSLLHDPCFLLLDEPTSGLDSKSAFDVIHILKSIAVSRQRTVILSIHQPSFKILSIIDRLLLLSKGTVVYHGRLDSLEGFLLFKGFTVPPQLNSLEYAMEILQELRESDGNTDATALPSIENRKQREKQSIVRYRKSRITEISLLARRFWKIIYRTRQLLLTNALEALVVGLVLGTIYINIGIGKAGIEKRFGMFAFTLTFLLSSTTETLPIFINERPILLRETSSGIYRLSSHILANTLVFLPYLFVISIIYSVSVYFLIGLCPTWQAFGYFVLVIWIILLMANSFVLFLSSLAPNYITGTSLVTILLAAFFLFSGYFISKESLPKYWLFMYFFSMYKYALDALLINEYSCLASKCLVWLEEAQTKICMVTGGDVLKKKGLHEKQRWFNVYVLLGFFVLYRVLCFLALLRRVSGSKR.
For Research Use Only | Not For Clinical Use.

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