Mouse Anti-Arabidopsis AT4G18710 Antibody (CBMOAB-17473FYC)
Cat: CBMOAB-17473FYC
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- Specifications
- Application Information
- Target
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | A. thaliana (Arabidopsis thaliana) |
Clone | MO17473FC |
Specificity | This antibody binds to Arabidopsis AT4G18710. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus; Other locations; Plasma Membrane; Cytosol |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Negative regulator in brassinosteroid signal transduction pathway important for plant growth. May be also involved in auxin signaling pathway. Phosphorylates and increases the degradation of BZR1 and BZR2/BES1 by the proteasome. Phosphorylates BHLH150, beet curly top virus C4 and tomato golden mosaic virus AC4 on threonine and serine residues. Upon brassinosteroid signaling, inhibits stomatal development by phosphorylating and inhibiting the MAPKK kinase YDA and the MAPK kinases MKK4 and MKK5 (PubMed:11847343, PubMed:12114546, PubMed:12427989, PubMed:17280695, PubMed:22307275, PubMed:23341468). Phosphorylates BSK1, BSK3, BSK5, BSK6, BSK8 AND BSK11 in vitro (PubMed:23496207). Phoyphorylates and destabilizes WRKY46, WRKY54 and WRKY70 (PubMed:28576847). Mediates BASL nuclear exclusion; kinase activity is required for this function (PubMed:30429609). Required first at the cortical polarity site, to restrict MAPK signaling and promote asymmetric cell division (ACD), and second in the nucleus of stomatal lineage ground cells (SLGCs) or meristemoids, to limit cell division and to promote differentiation into pavement or stomatal guard cells, respectively, likely by initiating BASL polarization (PubMed:30429609). Phosphorylates BASL, YDA and SPCH in vitro and POLAR in vivo (PubMed:30429609). Phosphorylates and inhibits SPCH in the nucleus of SLGC undergoing ACD, thus negatively regulating stomatal development (PubMed:30429609, PubMed:22466366). |
Product Overview | Mouse Anti-Arabidopsis AT4G18710 Antibody is a mouse antibody against AT4G18710. It can be used for AT4G18710 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | AT4G18710 protein; At4g18710 |
UniProt ID | C0Z326 |
Protein Refseq | The length of the protein is 374 amino acids long. The sequence is show below: MPAAVVDGHDQVTGHIISTTIGGKNGEPKQTISYMAERVVGTGSFGIVFQAKCLETGETVAIKKVLQDRRYKNRELQLMRVMDHPNVVCLKHCFFSTTSKDELFLNLVMEYVPESLYRVLKHYSSANQRMPLVYVKLYMYQIFRGLAYIHNVAGVCHRDLKPQNLLVDPLTHQVKICDFGSAKQLVKGEANISYICSRFYRAPELIFGATEYTTSIDIWSAGCVLAELLLGQPLFPGENAVDQLVEIIKVLGTPTREEIRCMNPHYTDFRFPQIKAHPWHKIFHKRMPPEAIDFASRLLQYSPSLRCTALEACAHPFFDELREPNARLPNGRPFPPLFNFKQEVAGSSPELVNKLIPDHIKRQLGLSFLNQSGT. |
For Research Use Only | Not For Clinical Use.
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