Mouse Anti-Arabidopsis TAF1 Antibody (CBMOAB-44770FYC)


Cat: CBMOAB-44770FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO44770FC
SpecificityThis antibody binds to Arabidopsis TAF1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N- and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. Mutations in this gene result in Dystonia 3, torsion, X-linked, a dystonia-parkinsonism disorder. Alternative splicing of this gene results in multiple transcript variants. This gene is part of a complex transcription unit (TAF1/DYT3), wherein some transcript variants share exons with TAF1 as well as additional downstream DYT3 exons.
Product OverviewMouse Anti-Arabidopsis TAF1 Antibody is a mouse antibody against TAF1. It can be used for TAF1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesTATA-Box Binding Protein Associated Factor 1; TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa; TBP-Associated Factor 250 KDa; Cell Cycle Gene 1 Protein; EC 2.7.11.1; TAF(II)250; TAFII-250; TAFII250; TAF2A; P250; BA2R; CCG1; CCGS; TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, A, 250kD; Transcription Initiation Factor TFIID 250 KDa Subunit; Transcription Initiation Factor TFIID Subunit 1
UniProt IDQ8LRK9
Protein RefseqThe length of the protein is 1919 amino acids long. The sequence is show below: MAESNGKGSHNETSSDDDDEYEDNSRGFNLGFIFGNVDNSGDLDADYLDEDAKEHLSALADKLGSSLPDINLLAKSERTASDPAEQDYDRKAEDAVDYEDIDEEYDGPEVQVVSEEDHLLPKKEYFSTAVALGSLKSRASVFDDEDYDEEEEQEEEQAPVEKSLETEKREPVVLKEDKALEYEEEASILDKEDHMDTEDVQEEEVDELLEGTLDDKGATPLPTLYVEDGMVILQFSEIFAIHEPPQKRDRRENRYVTCRDKYKSMDISELVEDDEEVLLKSHGRIDTHVEQADLIQLDVPFPIREGLQLVKASTIGGITPESREFTKLGRDSCIMGELLKQDFIDDNSSLCQSQLSMQVFPLDQHEWERRIIWEHSPEISGNSGEIFEPGLEPEGMLVKGTNSETEQESLNVVNSRVQVQADNNMFVPFSANLLESFGSRGSQSTNESTNKSRHHPQLLRLESQWDENHLSGNDEAGVKKIKRLEKDALGRFSRLVLRERDLGDEAWLDSIIWDSEKELSRSKLIFDLQDEQMVFEIFDNEESKNLQLHAGAMIVSRSSKSKDETFQEGCESNSGWQFNLSNDKFYMNGKSSQQLQANTNKSSVHSLRVFHSVPAIKLQTMKSKLSNKDIANFHRPKALWYPHDNELAIKQQGKLPTRGSMKIIVKSLGGKGSKLHVGIEESVSSLRAKASRKLDFKETEAVKMFYKGKELDDEKSLAAQNVQPNSLVHLIRTKVHLWPWAQKLPGENKSLRPPGAFKKKSDLSTKDGHVFLMEYCEERPLMLSNAGMGANLCTYYQKSSPEDQRGNLLRNQSDTLGNVMILEPGDKSPFLGEIHAGCSQSSVETNMYKAPIFPQRLQSTDYLLVRSPKGKLSLRRIDKIVVVGQQEPRMEVMSPGSKNLQTYLVNRMLVYVYREFFKRGGGEHPIAADELSFLFSNLTDAIIKKNMKIIACWKRDKNGQSYWTKKDSLLEPPESELKKLVAPEHVCSYESMLAGLYRLKHLGITRFTLPASISNALAQLPDEAIALAAASHIERELQITPWNLSSNFVACTNQDRANIERLEITGVGDPSGRGLGFSYVRAAPKAPAAAGHMKKKAAAGRGAPTVTGTDADLRRLSMEAAREVLIKFNVPDEIIAKQTRWHRIAMIRKLSSEQAASGVKVDPTTIGKYARGQRMSFLQMQQQAREKCQEIWDRQLLSLSAFDGDENESENEANSDLDSFAGDLENLLDAEEGGEGEESNISKNDKLDGVKGLKMRRRPSQVETDEEIEDEATEYAELCRLLMQDEDQKKKKKKMKGVGEGMGSYPPPRPNIALQSGEPVRKANAMDKKPIAIQPDASFLVNESTIKDNRNVDSIIKTPKGKQVKENSNSLGQLKKVKILNENLKVFKEKKSARENFVCGACGQHGHMRTNKHCPRYRENTESQPEGIDMDKSAGKPSSSEPSGLPKLKPIKNSKAAPKSAMKTSVDEALKGDKLSSKTGGLPLKFRYGIPAGDLSDKPVSEAPGSSEQAVVSDIDTGIKSTSKISKLKISSKAKPKESKGESERRSHSLMPTFSRERGESESHKPSVSGQPLSSTERNQAASSRHTISIPRPSLSMDTDQAESRRPHLVIRPPTEREQPQKKLVIKRSKEMNDHDMSSLEESPRFESRKTKRMAELAGFQRQQSFRLSENSLERRPKEDRVWWEEEEISTGRHREVRARRDYDDMSVSEEPNEIAEIRRYEEVIRSEREEEERQKAKKKKKKKKLQPEIVEGYLEDYPPRKNDRRLSERGRNVRSRYVSDFERDGAEYAPQPKRRKKGEVGLANILERIVDTLRLKEEVSRLFLKPVSKKEAPDYLDIVENPMDLSTIRDKVRKIEYRNREQFRHDVWQIKYNAHLYNDGRNPGIPPLADQLLEICDYLLDDYEDQLKEAEKGIDPND.
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For Research Use Only | Not For Clinical Use.
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