Mouse Anti-Arabidopsis TERT Antibody (CBMOAB-44925FYC)


Cat: CBMOAB-44925FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO44925FC
SpecificityThis antibody binds to Arabidopsis TERT.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionTelomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity.
Product OverviewMouse Anti-Arabidopsis TERT Antibody is a mouse antibody against TERT. It can be used for TERT detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesTelomerase Reverse Transcriptase; Telomerase-Associated Protein 2; Telomerase Catalytic Subunit; EC 2.7.7.49; HEST2; TCS1; EST2; TP2
UniProt IDQ9SPU7
Protein RefseqThe length of the protein is 1123 amino acids long. The sequence is show below: MPRKPRHRVPEILWRLFGNRARNLNDAIVDLIPNRNIQPEQCRCRGQGCLGCSSDKPAFLLRSDDPIHYRKLLHRCFVVLHEQTPPLLDFSPTSWWSQREIVERIIEMMQSGCDCQNVICARYDKYDQSSPILELLTSSSWEFLLKRVGHDVMVYLLQQTSIFLPLLGKKHQQVSGPPLCIKHKRTLSVHENKRKRDDNVQPPTKRQWLSSAVDDCPKDDSATITPIVGEDVDQHREKKTTKRSRIYLKRRRKQRKVNFKKVDCNAPCITPSTNGKVSTGNDEMNLHIGINGSLTDFVKQAKQVKRNKNFKFGLSETYSVIPPNHILKTLRPNCSDSKLLMNHIFGEVNVWSTTPSHGKGNCPSGSICLYHSLLKSLKNLIGKTKSSHLKMLLDKHCPVLLLQEDALKSGTTSQSSRRQKADKLPHGSSSSQTGKPKCPSVEERKLYCTNDQVVSFIWAICRYIVPESLLGTTHQMRVLRKNIAWFVSRRRNEKCTVNQFLHKVKPSDFPFFARKELCCMVNGHELQSESIRSTQQMLCTKWISWLFLEIVKKLVHFNFYATESQGGRLNIYYYRKRSWERLISKEISKALDGYVLVDDAEAESSRKKLSKFRFLPKANGVRMVLDFSSSSRSQSLRDTHAVLKDIQLKEPDVLGSSVFDHDDFYRNLCPYLIHLRSQSGELPPLYFVVADVFKAFDSVDQGKLLHVIQSFLKDEYILNRCRLVCCGKRSNWVNKILVSSDKNSNFSRFTSTVPYNALQSIVVDKGENHRVRKKDLMVWIGNMLKNNMLQLDKSFYVQIAGIPQGHRLSSLLCCFYYGHLERTLIYPFLEEASKDVSSKECSREEELIIPTSYKLLRFIDDYLFVSTSRDQASSFYHRLKHGFKDYNCFMNETKFCINFEDKEEHRCSSNRMFVGDNGVPFVRWTGLLINSRTFEVQVDYTRYLSGHISSTFSVAWQNKPVRNLRQKLCYFLVPKCHPILFDSNINSGEIVRLNIYQIFLLAAMKFHCYVYEVSRFWKLHPQTLFKFITISVRYMFRLINRRVRRINTGSSFRPVLKLYKEEVIWLGLDAYIQVLKKKNSRYRMLLIYLKSALSKHSLSQQLSSELRYATDRSNSSSLWKLNY.
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For Research Use Only | Not For Clinical Use.
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