Mouse Anti-ASAH1 Antibody (CBMOAB-00673HCB)
Cat: CBMOAB-00673HCB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-00673HCB | Monoclonal | C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rhesus (Macaca mulatta) | WB, ELISA | MO00673HB | 100 µg | ||
| CBMOAB-36337FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO36337FYA | 100 µg | ||
| MO-AB-07666R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO07666R | 100 µg | ||
| MO-AB-21491W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO21491W | 100 µg | ||
| MO-AB-51359W | Monoclonal | Marmoset | WB, ELISA | MO51359W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rhesus (Macaca mulatta) |
| Clone | MO00673HB |
| Specificity | This antibody binds to C. elegans ASAH1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Extracellular region or secreted; Lysosome |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. |
| Product Overview | Mouse Anti-C. elegans ASAH1 Antibody is a mouse antibody against ASAH1. It can be used for ASAH1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Acid ceramidase; EC 3.5.1.23; Acylsphingosine amidohydrolase 1; asah-1 |
| Gene ID | 173120 |
| UniProt ID | O45686 |
| Protein Refseq | The length of the protein is 393 amino acids long. The sequence is show below: MLRELSVLLLVAVCAAKHVELPAPFKDHCILDDKQNLYDPSKQFDIKWYDVNLDLPPSERWVQIATANKEHIADLIGVLINLITPWFPNAIDFVDDVFGDLAPKLAQPYRDEIFSIANATGIPLGQITMYNIFYEIFTVCTSVIAQDKDGHVFHARNLDFGLFMGWDPVLHDWQISQKLRKMIINVNWLKDGKLLYKSNNFAGYIGIYNGLKPNAFSLTADDRFQLVGGYYGILKWVFGLEADGKWMSWLARETLETKTTYLDAKEHLMNTPMLSPVYFILGGSKKDEGCIIARSLDKTALLTEMATSPHGWYLLETNYDQGTEDLYLDDRDTPGFRCMDKLTQKNVGFEGIFNVLSSRTNLNKLTTYTVLMSVETSRFETILQSCPGECYPW. |
For Research Use Only | Not For Clinical Use.
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