Mouse Anti-ASH2 Antibody (CBMOAB-00690HCB)
Cat: CBMOAB-00690HCB
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-00690HCB | Monoclonal | C. elegans (Caenorhabditis elegans), Fruit fly (Drosophila melanogaster), Silkworm (Bombyx mori) | WB, ELISA | MO00690HB | 100 µg | ||
CBMOAB-01282FYA | Monoclonal | Fruit fly (Drosophila melanogaster) | WB, ELISA | MO01282FYA | 100 µg | ||
MO-AB-68835W | Monoclonal | Silkworm (Bombyx mori) | WB, ELISA | MO68835W | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | C. elegans (Caenorhabditis elegans), Fruit fly (Drosophila melanogaster), Silkworm (Bombyx mori) |
Clone | MO00690HB |
Specificity | This antibody binds to C. elegans ASH2. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Component of the set-2/ash-2 histone methyltransferase (HMT) complex (Probable). Required for the di- and trimethylation at ''Lys-4'' of histone H3, a mark associated with epigenetic transcriptional activation (PubMed:21527717, PubMed:20555324). Implicated in the epigenetic inheritance of lifespan over several generations (PubMed:22012258). Functions as transcriptional regulator (PubMed:28379943). Acts in the germline to limit the longevity of the soma, probably by regulating a lipid metabolism pathway that signals from the germline to the intestine, thereby preventing accumulation of mono-unsaturated fatty acids (PubMed:20555324, PubMed:22012258, PubMed:28379943). |
Product Overview | Mouse Anti-C. elegans ASH2 Antibody is a mouse antibody against ASH2. It can be used for ASH2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Protein ASH-2, isoform b; ash-2 |
Gene ID | 174838 |
UniProt ID | Q9XXH4 |
Protein Refseq | The length of the protein is 572 amino acids long. The sequence is show below: MRSSKGGRGRQAAPKTAPTTVCYCDGKRELGSVEVVCSTCLKWFHGRCLKEFHEFSRNSNGVPFMICYTFTCKQCRPTAEDWKAKKADLVQMCVTVLATLSAERLKADGKLSAEHVPEDFTYLSLKDEIVPYMNENWYMLTAIKQKKEWHQNLAPTLLKEKNIFVQHNDDDDLFALAEKNLSLLGPLHEAVKLIGKRPIERENREPRHIELPPIEGPKTRGASKRRHAEAPVTGKKQKLAADYSSTAAPNGVQIDIPFSKDNYRYYLTEVDPNVPEDPAWNQNQSSAYVIPSFHYRELLNPTVNVSSNDRAFQLSINGNSITGFEGYSMARASHGVSKGTWYFEVNFDDQPDDSHIRIGWSQSYASLQACVGYNKFSYGWRSKHGTKFHEAKGKKYHFGGFKQGDVLGCLIHLPVDKKLQIPANLPSEKYLPVSHKGFNLISFKANYFFEVQEESADIAKTLVEMPGSYIEFFHNGKSCGKAYENIYAGAYYPSISIFKSATATMNLGPKFRNLPRGATGIHARADEQQHEQTLSDMLYLVSKEVNLDHPPRVKREDDDDVKDIKKEIKQEI. |
For Research Use Only | Not For Clinical Use.
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