Mouse Anti-ASH2 Antibody (CBMOAB-00690HCB)


Cat: CBMOAB-00690HCB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-00690HCB Monoclonal C. elegans (Caenorhabditis elegans), Fruit fly (Drosophila melanogaster), Silkworm (Bombyx mori) WB, ELISA MO00690HB 100 µg
CBMOAB-01282FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO01282FYA 100 µg
MO-AB-68835W Monoclonal Silkworm (Bombyx mori) WB, ELISA MO68835W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), Fruit fly (Drosophila melanogaster), Silkworm (Bombyx mori)
CloneMO00690HB
SpecificityThis antibody binds to C. elegans ASH2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of the set-2/ash-2 histone methyltransferase (HMT) complex (Probable). Required for the di- and trimethylation at ''Lys-4'' of histone H3, a mark associated with epigenetic transcriptional activation (PubMed:21527717, PubMed:20555324). Implicated in the epigenetic inheritance of lifespan over several generations (PubMed:22012258). Functions as transcriptional regulator (PubMed:28379943). Acts in the germline to limit the longevity of the soma, probably by regulating a lipid metabolism pathway that signals from the germline to the intestine, thereby preventing accumulation of mono-unsaturated fatty acids (PubMed:20555324, PubMed:22012258, PubMed:28379943).
Product OverviewMouse Anti-C. elegans ASH2 Antibody is a mouse antibody against ASH2. It can be used for ASH2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein ASH-2, isoform b; ash-2
Gene ID174838
UniProt IDQ9XXH4
Protein RefseqThe length of the protein is 572 amino acids long. The sequence is show below: MRSSKGGRGRQAAPKTAPTTVCYCDGKRELGSVEVVCSTCLKWFHGRCLKEFHEFSRNSNGVPFMICYTFTCKQCRPTAEDWKAKKADLVQMCVTVLATLSAERLKADGKLSAEHVPEDFTYLSLKDEIVPYMNENWYMLTAIKQKKEWHQNLAPTLLKEKNIFVQHNDDDDLFALAEKNLSLLGPLHEAVKLIGKRPIERENREPRHIELPPIEGPKTRGASKRRHAEAPVTGKKQKLAADYSSTAAPNGVQIDIPFSKDNYRYYLTEVDPNVPEDPAWNQNQSSAYVIPSFHYRELLNPTVNVSSNDRAFQLSINGNSITGFEGYSMARASHGVSKGTWYFEVNFDDQPDDSHIRIGWSQSYASLQACVGYNKFSYGWRSKHGTKFHEAKGKKYHFGGFKQGDVLGCLIHLPVDKKLQIPANLPSEKYLPVSHKGFNLISFKANYFFEVQEESADIAKTLVEMPGSYIEFFHNGKSCGKAYENIYAGAYYPSISIFKSATATMNLGPKFRNLPRGATGIHARADEQQHEQTLSDMLYLVSKEVNLDHPPRVKREDDDDVKDIKKEIKQEI.
For Research Use Only | Not For Clinical Use.
Online Inquiry