Mouse Anti-ASNA1 Antibody (CBMOAB-00697HCB)


Cat: CBMOAB-00697HCB
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-00697HCB Monoclonal C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Gorilla, Guinea pig (Cavia porcellus), Hamsters (Cricetinae), Marmoset, Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, ELISA MO00697HB 100 µg
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CBMOAB-36385FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO36385FYA 100 µg
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CBMOAB-66783FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO66783FYA 100 µg
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MO-AB-00107L Monoclonal Elephant (Loxodonta africana) WB, ELISA MO00107L 100 µg
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MO-AB-10677W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO10677W 100 µg
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MO-AB-14266Y Monoclonal Sheep (Ovis aries) WB, ELISA MO14266Y 100 µg
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MO-AB-34420W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO34420W 100 µg
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MO-AB-38446W Monoclonal Gorilla WB, ELISA MO38446W 100 µg
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MO-AB-41269W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO41269W 100 µg
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MO-AB-42940W Monoclonal Hamsters (Cricetinae) WB, ELISA MO42940W 100 µg
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MO-AB-51401W Monoclonal Marmoset WB, ELISA MO51401W 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Gorilla, Guinea pig (Cavia porcellus), Hamsters (Cricetinae), Marmoset, Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMO00697HB
SpecificityThis antibody binds to C. elegans ASNA1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationEndoplasmic reticulum; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting. (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-C. elegans ASNA1 Antibody is a mouse antibody against ASNA1. It can be used for ASNA1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesATPase asna-1; Arsenical pump-driving ATPase; Arsenite-stimulated ATPase; asna-1
Gene ID176254
UniProt IDP30632
Protein RefseqThe length of the protein is 342 amino acids long. The sequence is show below: MSDQLEASIKNILEQKTLKWIFVGGKGGVGKTTCSCSLAAQLSKVRERVLLISTDPAHNISDAFSQKFTKTPTLVEGFKNLFAMEIDSNPNGEGVEMGNIEEMLQNAAQNEGGSGGFSMGKDFLQSFAGGLPGIDEAMSFGEMIKLIDSLDFDVVVFDTAPTGHTLRLLQFPTLLEKVFTKILSLQGMFGPMMNQFGGMFGMGGGSMNEMIEKMTTTLESVKKMNAQFKDPNCTTFVCVCIAEFLSLYETERLIQELSKQGIDTHNIIVNQLLFPDTDANGTVSCRKCASRQAIQSKYLTDIDELYEDFHVVKLPLLEAEVRGGPAILQFSERMVDPEANKN.
For Research Use Only | Not For Clinical Use.
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