Mouse Anti-ATF6 Antibody (CBMOAB-00730HCB)
Cat: CBMOAB-00730HCB
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-00730HCB | Monoclonal | C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Marmoset, O. mykiss (Oncorhynchus mykiss), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) | WB, ELISA | MO00730HB | 100 µg | ||
CBMOAB-01979FYA | Monoclonal | Fruit fly (Drosophila melanogaster) | WB, ELISA | MO01979FYA | 100 µg | ||
CBMOAB-36474FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO36474FYA | 100 µg | ||
CBMOAB-66877FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO66877FYA | 100 µg | ||
MO-AB-01679H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO01679C | 100 µg | ||
MO-AB-07741R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO07741R | 100 µg | ||
MO-AB-10683Y | Monoclonal | O. mykiss (Oncorhynchus mykiss) | WB, ELISA | MO10683Y | 100 µg | ||
MO-AB-14276Y | Monoclonal | Sheep (Ovis aries) | WB, ELISA | MO14276Y | 100 µg | ||
MO-AB-17612W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO17612W | 100 µg | ||
MO-AB-23904R | Monoclonal | Pig (Sus scrofa) | WB, ELISA | MO23904R | 100 µg | ||
MO-AB-51447W | Monoclonal | Marmoset | WB, ELISA | MO51447W | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Marmoset, O. mykiss (Oncorhynchus mykiss), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) |
Clone | MO00730HB |
Specificity | This antibody binds to C. elegans ATF6. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. (From NCBI) |
Product Overview | Mouse Anti-C. elegans ATF6 Antibody is a mouse antibody against ATF6. It can be used for ATF6 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Protein ATF-6; atf-6 |
Gene ID | 181405 |
UniProt ID | Q20435 |
Protein Refseq | The length of the protein is 589 amino acids long. The sequence is show below: MNFDNTVHESNFDDLLHNPNFPPQFDQLELDSLLYGTDESQESTSSSSFGFSDQNAGFRSRDGGSLGDSSSDSSPPLSCANFTENDQEMWDFGFQSRSPFENFEQQFGSPYQDDEVIAEPTNEFMNARYLREEPAKHLPMQQKRIITILPKQSQPVKRIVSRPIQKVYRVKESPGSQQQTYRVVQPLMPSPSQATQRQIKQMYYNEPVQEIHMQPKSGPLVRQVSEEPRYVPIAPTVDIKAEPQVFTSEQNRKIRNRMYAQASRMRKKEADEHMKMNLQELLQENEILRTENAALKQRLAFFEHEEPVVEVPQPFGRNQKKKRIIAAGSVLMMFGLFAVISPFNVDNNLNINNQIMAISNETSMVARHGRVITYEDSAPVAKIPTQQPIHNYPNSTQNDCDMYKLNATETIRVNNDIERWVQVHSFDNVPMKFSGGLLNKEAMRKFNYAQKVKPASVYGPQTLAVQKKSEQAALRSRERTWKQLDLLKTGNNIQLDNEKIQRKRQDIDKIASIVRQKGDTLYIMTLQDYVLLPSLIKGANSVPKLSLLLPSVPMNGTLQDQYTLLRVDCEVTGTGQLTLSNKQLSYLMP. |
For Research Use Only | Not For Clinical Use.
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