Mouse Anti-ATG4A Antibody (CBMOAB-24517FYC)


Cat: CBMOAB-24517FYC
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Lot Number

  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-24517FYC Monoclonal A. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Marmoset, Rhesus (Macaca mulatta), Rice (Oryza), Zebrafish (Danio rerio) WB, ELISA MO24517FC 100 µg
CBMOAB-02005FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO02005FYA 100 µg
CBMOAB-36495FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO36495FYA 100 µg
CBMOAB-66916FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO66916FYA 100 µg
CBMOAB-18700FYB Monoclonal Rice (Oryza) WB, ELISA MO18700FYB 100 µg
MO-AB-16855W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO16855W 100 µg
MO-AB-51468W Monoclonal Marmoset WB, ELISA MO51468W 100 µg
MO-AB-07751R Monoclonal Cattle (Bos taurus) WB, ELISA MO07751R 100 µg
MO-AB-01682H Monoclonal Frog (Xenopus laevis) WB, ELISA MO01682C 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Marmoset, Rhesus (Macaca mulatta), Rice (Oryza), Zebrafish (Danio rerio)
CloneMO24517FC
SpecificityThis antibody binds to Arabidopsis ATG4A.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.
Product OverviewMouse Anti-Arabidopsis ATG4A Antibody is a mouse antibody against ATG4A. It can be used for ATG4A detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAutophagy Related 4A Cysteine Peptidase; Autophagy-Related Cysteine Endopeptidase 2; Autophagy-Related Protein 4 Homolog A; HAPG4A; APG4A; AUTL2; AUT-Like 2, Cysteine Endopeptidase (S. Cerevisiae); ATG4 Autophagy Related 4 Homolog A (S. Cerevisiae); APG4 Autophagy 4 Homolog A (S. Cerevisiae); Autophagy Related 4A, Cysteine Peptidase
UniProt IDQ8S929
Protein RefseqThe length of the protein is 467 amino acids long. The sequence is show below: MKALCDRFVPQQCSSSSKSDTHDKSPLVSDSGPSDNKSKFTLWSNVFTSSSSVSQPYRESSTSGHKQVCTTRNGWTAFVKRVSMASGAIRRFQERVLGPNRTGLPSTTSDVWLLGVCYKISADENSGETDTGTVLAALQLDFSSKILMTYRKGFEPFRDTTYTSDVNWGCMIRSSQMLFAQALLFHRLGRAWTKKSELPEQEYLETLEPFGDSEPSAFSIHNLIIAGASYGLAAGSWVGPYAICRAWESLACKKRKQTDSKNQTLPMAVHIVSGSEDGERGGAPILCIEDATKSCLEFSKGQSEWTPIILLVPLVLGLDSVNPRYIPSLVATFTFPQSVGILGGKPGASTYIVGVQEDKGFYLDPHEVQQVVTVNKETPDVDTSSYHCNVLRYVPLESLDPSLALGFYCRDKDDFDDFCLRALKLAEESNGAPLFTVTQTHTAINQSNYGFADDDSEDEREDDWQML.

Reference

Reference1. Yoshimoto, K., Hanaoka, H., Sato, S., Kato, T., Tabata, S., Noda, T., & Ohsumi, Y. (2004). Processing of ATG8s, ubiquitin-like proteins, and their deconjugation by ATG4s are essential for plant autophagy. The Plant Cell, 16(11), 2967-2983.
2. Aroca, A., & Gotor, C. (2022). Hydrogen sulfide action in the regulation of plant autophagy. FEBS letters, 596(17), 2186-2197.
3. Tang, J., & Bassham, D. C. (2022). Autophagy during drought: function, regulation, and potential application. The Plant Journal, 109(2), 390-401.
For Research Use Only | Not For Clinical Use.
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