Rabbit Anti-b2m Antibody (MOFY-1222-FY240)
Cat: MOFY-1222-FY240
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
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- Product Details
Specifications
| Host species | Rabbit |
| Species Reactivity | African clawed frog |
| Format | Liquid or Lyophilized |
| Buffer | PBS, 50% glycerol |
| Regulatory Status | For Research Use Only. Not For Clinical Use. |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | WB, IHC, ICC, IF, ELISA |
Target
| Introduction | The serum protein encoded by this gene is associated with the major histocompatibility complex (MHC) class I heavy chain on the surface of almost all nucleated cells. The protein mainly has a β-sheet structure that can form amyloid fibrils under certain pathological conditions. The encoded antimicrobial protein exhibits antimicrobial activity in amniotic fluid. Mutations in this gene have been shown to cause hypercatabolic hypoproteinemia. [Provided by RefSeq, Aug 2014] B2M (beta-2-microglobulin) is a protein-coding gene. Diseases associated with B2M include immunodeficiency43 and amyloidosis, a familial visceral disorder. Its related pathways include cytokine signaling in the immune system and the innate immune system. Gene Ontology (GO) annotations associated with this gene include the same protein binding. Component of class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenous M. tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in the host) binds B2M and reduces its export to the cell surface (total protein levels are unchanged), possibly resulting in defective class I antigen presentation (PubMed: 25356553 ). |
| Alternative Names | B2M; beta 2Microglobulin; beta 2-Microglobulin; beta chain of MHC class I molecules; beta-2-microglobin; beta-2-microglobulin B2M IMD43 beta-2-microglobulin beta-2-microglobulin; beta chain of MHC class I molecules; beta-2-microglobin |
| Gene ID | 567 |
| UniProt ID | P61769 |
See other products for " B2m "
| MO-AB-10714Y | Mouse Anti-O. mykiss B2m Antibody (MO-AB-10714Y) |
| MO-AB-08050W | Mouse Anti-Cat B2M Antibody (MO-AB-08050W) |
| MO-AB-34163W | Mouse Anti-Donkey B2M Antibody (MO-AB-34163W) |
| MO-AB-32874H | Mouse Anti-Nile tilapia B2m Antibody (MO-AB-32874H) |
| MO-AB-42954W | Mouse Anti-Hamsters B2M Antibody (MO-AB-42954W) |
| MO-AB-29195W | Mouse Anti-Dog B2M Antibody (MO-AB-29195W) |
| MOFY-0722-FY428 | Rabbit Anti-b2M Antibody (MOFY-0722-FY428) |
| MOFY-0722-FY183 | Rabbit Anti-b2M Antibody (MOFY-0722-FY183) |
| MO-AB-34450W | Mouse Anti-Ferret B2M Antibody (MO-AB-34450W) |
| MO-DKB-01167W | Rabbit Anti-B2M Antibody (MO-DKB-01167W) |
For Research Use Only | Not For Clinical Use.
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