Mouse Anti-B5r Antibody (MO-AB-00255Y)
Cat: MO-AB-00255Y
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| MO-AB-00255Y | Monoclonal | Chicken (Gallus gallus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Dog (Canis lupus familiaris), Primate, Frog (Xenopus), Zebrafish (Danio rerio) | WB, ELISA | MO00255Y | 100 µg | ||
| MO-NAB-00453W | Monoclonal | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Dog (Canis lupus familiaris), Chicken (Gallus gallus), Primate, Frog (Xenopus), Zebrafish (Danio rerio) | WB | NW0378 | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Chicken (Gallus gallus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Dog (Canis lupus familiaris), Primate, Frog (Xenopus), Zebrafish (Danio rerio) |
| Clone | MO00255Y |
| Specificity | This antibody binds to Chicken B5r. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Some engineered VV strains produce large amounts of EEV (e.g., International Health Department (IHD)-J, vA34R, or WI) due to a point mutation in glycoprotein A34R, making them suitable for oncolytic virotherapy. However, EEV has only partial immune resistance, although it is higher than that of IMV. Of the five EEV outer membrane surface antigens (A33R, A34R, A36R, A56R, and B5R), B5R is the most frequent target of host-neutralizing antibodies. B5R is a 42-kDa envelope glycoprotein containing four short consensus repeat (SCR) domains, whose expression is critical for viral morphogenesis, trafficking, dissemination, and EEV production. However, anti-B5R antibody recognizing the SCR1/SCR2 boundary and/or the B5R stalk region26 induces complement-dependent EEV neutralization. |
| Product Overview | This product is a mouse antibody against B5r. It can be used for B5r detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | NADH-cytochrome b5 reductase; b5r |
| UniProt ID | Q9DEQ7 |
| Protein Refseq | The length of the protein is 178 amino acids long. The sequence is show below: GGKMSQYLDSMKIGDVIDFRGPNGLLVYKGSGTFMIKPDKKSDAQRKFAKHLGMIAGGTGITPMLQLIRHITSDPKDSTKCYLLFANQTEKDILLRAELEDIAKRHPDQVRLWYTLDRPPQDWKYSSGFVTADMIKTHLPPPGGETLILMCGPPPMIQFACQPNLDKLGYPKSSTFSY. |
For Research Use Only | Not For Clinical Use.
Online Inquiry