Mouse Anti-C. elegans ACMSD Antibody (CBMOAB-00290HCB)


Cat: CBMOAB-00290HCB
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO00290HB
SpecificityThis antibody binds to C. elegans ACMSD.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Product OverviewMouse Anti-C. elegans ACMSD Antibody is a mouse antibody against ACMSD. It can be used for ACMSD detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; EC 4.1.1.45; Picolinate carboxylase; acmsd
UniProt IDQ8T8B9
Protein RefseqThe length of the protein is 401 amino acids long. The sequence is show below: MPICEFSATSKSRKIDVHAHVLPKNIPDFQEKFGYPGFVRLDHKEDGTTHMVKDGKLFRVVEPNCFDTETRIADMNRANVNVQCLSTVPVMFSYWAKPADTEIVARFVNDDLLAECQKFPDRLVPLGTLPMNDVQRAVEIFGKRIFFFEIWSPAKKSPEEVKRCVSMGIKGFEVGSHVAEKSLDHRDFWPLYKLTESFKLSTIMPGFCEFFENWGLTTKTPGICEELSVVLFVHPWDMHMWDGRLDKYWMPWLVGMPSETAQAICSVLMGNILVLFPKLKLCFAHGGGAYPQIRGRVSHGWNVRPDLCAGKCKVAPNKLDGLLWTDSLVHDPKALELLINTVGKEHIVLGTDYPFPLGELEVGRVVEEYKPFSAKDREDLLWKNAVKMLDIDENLLFNKDF.
For Research Use Only | Not For Clinical Use.
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