Mouse Anti-C. elegans APH1 Antibody (CBMOAB-00565HCB)


Cat: CBMOAB-00565HCB
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  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO00565HB
SpecificityThis antibody binds to C. elegans APH1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Endoplasmic reticulum; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionEssential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors (lin-12 or glp-1). It may represent a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Required for the localization of aph-2.
Product OverviewMouse Anti-C. elegans APH1 Antibody is a mouse antibody against APH1. It can be used for APH1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGamma-secretase subunit aph-1; Anterior-pharynx-defective protein 1; Presenilin enhancer protein 1; aph-1
Gene ID172747
UniProt IDO45876
Protein RefseqThe length of the protein is 308 amino acids long. The sequence is show below: MGYLLTIACYIASFSPSIALFCSFIAHDPVRIILFFLGSFFWLVSLLFSSLAWLGLSTVLPDTFLLSLTVCIIAQELSRVAYFMLLKKAQRGLNKITRQGQISVAPGVSDLHNARHMLALVCGLGMGVISALFYTMNAFAIFSGPGTIGLPNALKTGEIDTNRAGKYLPLCYTLSAILLTLFHVTWTIMVWDSCHKIGRIPSAFVPGAAAVVSHLLVTFLSSLNSRGFHVLVFAVQFLILLICIAYCNVIMGGTISSFVNGIGQSITDAVTLKQVRTLIEERKLRTQRQSVPDEPMTERAGTSNTVNA.
See other products for " APH1 "
For Research Use Only | Not For Clinical Use.
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