Mouse Anti-ATF6 Antibody (CBMOAB-00730HCB)


Cat: CBMOAB-00730HCB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-00730HCB Monoclonal C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Marmoset, O. mykiss (Oncorhynchus mykiss), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, ELISA MO00730HB 100 µg
CBMOAB-01979FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO01979FYA 100 µg
CBMOAB-36474FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO36474FYA 100 µg
CBMOAB-66877FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO66877FYA 100 µg
MO-AB-01679H Monoclonal Frog (Xenopus laevis) WB, ELISA MO01679C 100 µg
MO-AB-07741R Monoclonal Cattle (Bos taurus) WB, ELISA MO07741R 100 µg
MO-AB-10683Y Monoclonal O. mykiss (Oncorhynchus mykiss) WB, ELISA MO10683Y 100 µg
MO-AB-14276Y Monoclonal Sheep (Ovis aries) WB, ELISA MO14276Y 100 µg
MO-AB-17612W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO17612W 100 µg
MO-AB-23904R Monoclonal Pig (Sus scrofa) WB, ELISA MO23904R 100 µg
MO-AB-51447W Monoclonal Marmoset WB, ELISA MO51447W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Fruit fly (Drosophila melanogaster), Marmoset, O. mykiss (Oncorhynchus mykiss), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMO00730HB
SpecificityThis antibody binds to C. elegans ATF6.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. (From NCBI)
Product OverviewMouse Anti-C. elegans ATF6 Antibody is a mouse antibody against ATF6. It can be used for ATF6 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein ATF-6; atf-6
Gene ID181405
UniProt IDQ20435
Protein RefseqThe length of the protein is 589 amino acids long. The sequence is show below: MNFDNTVHESNFDDLLHNPNFPPQFDQLELDSLLYGTDESQESTSSSSFGFSDQNAGFRSRDGGSLGDSSSDSSPPLSCANFTENDQEMWDFGFQSRSPFENFEQQFGSPYQDDEVIAEPTNEFMNARYLREEPAKHLPMQQKRIITILPKQSQPVKRIVSRPIQKVYRVKESPGSQQQTYRVVQPLMPSPSQATQRQIKQMYYNEPVQEIHMQPKSGPLVRQVSEEPRYVPIAPTVDIKAEPQVFTSEQNRKIRNRMYAQASRMRKKEADEHMKMNLQELLQENEILRTENAALKQRLAFFEHEEPVVEVPQPFGRNQKKKRIIAAGSVLMMFGLFAVISPFNVDNNLNINNQIMAISNETSMVARHGRVITYEDSAPVAKIPTQQPIHNYPNSTQNDCDMYKLNATETIRVNNDIERWVQVHSFDNVPMKFSGGLLNKEAMRKFNYAQKVKPASVYGPQTLAVQKKSEQAALRSRERTWKQLDLLKTGNNIQLDNEKIQRKRQDIDKIASIVRQKGDTLYIMTLQDYVLLPSLIKGANSVPKLSLLLPSVPMNGTLQDQYTLLRVDCEVTGTGQLTLSNKQLSYLMP.
For Research Use Only | Not For Clinical Use.
Online Inquiry