AibGenesis™ Mouse Anti-C. elegans saeg-2 Antibody (CBMOAB-58931FYC)
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- Specifications
- Application Information
- Target
- Relate Reference Data
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans) |
| Clone | MO58931FYC |
| Specificity | This antibody binds to C. elegans saeg-2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | As a likely component of a histone deacetylase complex, together with saeg-1 and hda-2, functions downstream of the cAMP-dependent kinase egl-4 to regulate the expression of genes required for egg-laying and foraging (PubMed:21573134). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-C. elegans saeg-2 (clone MO58931FYC) Antibody (CBMOAB-58931FYC) is a mouse antibody against saeg-2. It can be used for saeg-2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Uncharacterized protein T23G5.6; saeg-2 |
| UniProt ID | Q03615 |
| Protein Refseq | The length of the protein is 305 amino acids long. The sequence is show below: MRIVILDELLSREMDGSNDGSSARVNSLKHVIKRNKMDMADDAPSSLDLMRRIFQAEISREIHQIMERHTRTTLLPAIENLRKNGHVVDESVLNGLYCNILEAAKKPYQKDPEPMPPICTNGNGFLDINSQEHENNLKRGYESDSSDVSGVSHCSDAKRRRGRPRKDEEAYRLEMTPPTMNEVIRWNPDRIDVNTRFITATKIAQVMGMPPSILFNKYPRMFRYSCDEDDKNILHEQNLLIRAPGRCYLLVAEDARQLVPSTYFQDVLNVSFLISEPLLSKIRQKAASTYEKYKVFLPTQPNNYL. |
Relate Reference Data
IP
Figure 1 Physical interaction between EGL-4, SAEG-1, SAEG-2, and their mammalian orthologs. Co-immunoprecipitation of FLAG-tagged SAEG-2 (FLAG-SAEG-2) with HA-tagged SAEG-1 (HA-SAEG-1) or SAEG-2 (HA-SAEG-2) upon co-expression in Drosophila S2 cells.
IF
Figure 2 SAEG-1 and SAEG-2 act downstream of EGL-4 to control foraging behavior. Nuclear localization of SAEG-2::GFP fusion protein. Confocal image of a larval L4 stage saeg-2; hjSi15[saeg-2p::saeg-2::gfp] animal is shown. Inset shows the same animal at higher magnification, bracket indicates nuclei of neurons in the nerve ring and arrow indicates an intestinal nucleus.
IP
Figure 3 HDA-2 is part of the SAEG-1/SAEG-2 complex that mediates EGL-4 activity. Co-immunoprecipitation of FLAG-tagged HDA-2 with HA-tagged SAEG-2 after co-expression in Drosophila S2 cells.
IF
Figure 4 SAEG-1 and SAEG-2 act downstream of EGL-4 to control foraging behavior.