AibGenesis™ Mouse Anti-C. elegans SKR1 Antibody (CBMOAB-09791HCB)


Cat: CBMOAB-09791HCB

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  • Specifications
  • Application Information
  • Target

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO09791HB
SpecificityThis antibody binds to C. elegans SKR1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionProbable essential component of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:17626846). Regulates cell proliferation during embryonic and larval development (PubMed:11864567, PubMed:11864566). Involved in synapse elimination in early synapse development (PubMed:17626846). May negatively regulate the apoptotic activity of cep-1 in response to genotoxic stress (PubMed:18340346). Plays a role in sex determination (PubMed:18718460). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-C. elegans SKR1 Antibody is a mouse antibody against SKR1. It can be used for SKR1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein SKR-1; skr-1
UniProt IDG5ECU1
Protein RefseqThe length of the protein is 176 amino acids long. The sequence is show below: MADQKKVSEAAKEREIKISSSDNEIFLVPRNVIRLSNTINTLLMDLGLDDEEGTNAEPIPVQNVTASILKKVISWCNHHHSDPISTEDSDNREKRTDDIGSWDVEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGKSPEEIRRTFNIKNDFTPEEEEQIRKENAWCED.
For Research Use Only | Not For Clinical Use.
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