Mouse Anti-Cattle DDB2 Antibody (MO-AB-11256R)


Cat: MO-AB-11256R
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
CloneMO11256R
SpecificityThis antibody binds to Cattle DDB2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
Product OverviewMouse Anti-Cattle DDB2 Antibody is a mouse antibody against DDB2. It can be used for DDB2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesDNA damage-binding protein 2; Damage-specific DNA-binding protein 2; DDB2
UniProt IDQ0VBY8
Protein RefseqThe length of the protein is 426 amino acids long.
The sequence is show below: MAPRKRPENQKTPEVVVRPKSKRNRSPRELEPEAKKLCVKGPGSSRRFDSGLWAGLASLRVPPLCSSIVRALHQHKLGTAAWPSLQQGLQQSFLNSLASYRIFQKAAPFDRRATSLAWHPTHPSTLAVGSKGGDILLWNFGIKDKPTFIKGIGAGGSITGMKFNPLNTNQFFTSSMEGTTRLQDFKGNTLRVFASSDTCNVWFCSLDVSVKSRVVVTGDNVGHVILLNMDGRELWNLRMHKKKVTHVALNPCCDW.
For Research Use Only | Not For Clinical Use.
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