Mouse Anti-Cattle EpoR Antibody (MO-AB-12089R)


Cat: MO-AB-12089R
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
CloneMO12089R
SpecificityThis antibody binds to Cattle EpoR.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Product OverviewMouse Anti-Cattle EpoR Antibody is a mouse antibody against EpoR. It can be used for EpoR detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesErythropoietin receptor, Fragment; EpoR
UniProt IDQ28206
Protein RefseqThe length of the protein is 229 amino acids long.
The sequence is show below: DLVCFWEEAATAGVGPDNYSFSYQLEGEPWKPCRLHQAPTARGLVRFWCSLPTADTSSFVPLELHVTAASGASRHRRTIHVNEVVLLDPPARLVARRADEGGHVVLRWLPPPGAPMASLIRYEVNISAENAAGSAQRVEILDGRTECLLSNLRGGTRYTFMVRARMAEPSFGGFWSAWSEPASLLTASDLDPLILTLSLVLVLILLLLAVLALLSHRRTLKQKIWPGIP.
For Research Use Only | Not For Clinical Use.
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