Mouse Anti-Cattle ITGB1 Antibody (MO-AB-14331R)
Cat: MO-AB-14331R
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Cattle (Bos taurus) |
| Clone | MO14331R |
| Specificity | This antibody binds to Cattle ITGB1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma membrane; Endosome; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Integrin β-1 (ITGB1), also known as CD29, is a cell surface receptor encoded by the ITGB1 gene. The integrin binds to integrin α1 and integrin α2 to form an integrin complex that functions as a collagen receptor. It also forms a dimer with integrin α3, thereby forming integrin receptors for netrin 1 and reelin. These and other integrin β1 complexes have historically been called very late activation (VLA) antigens.Integrin β1 is expressed as at least four different isoforms. In cardiac and skeletal muscles, integrin β-1D isoforms are specifically expressed and located in the ribs, where they contribute to the lateral force transmission from the Z disk to the extracellular matrix. Abnormal levels of integrin β-1D were found in limb-girdle muscular atrophy and polyneuropathy. |
| Product Overview | Mouse Anti-Cattle ITGB1 Antibody is a mouse antibody against ITGB1. It can be used for ITGB1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Integrin beta-1; Fibronectin receptor subunit beta; VLA-4 subunit beta; CD antigen CD29; ITGB1 |
| UniProt ID | P53712 |
| Protein Refseq | The length of the protein is 798 amino acids long. The sequence is show below: MNLQLIFWIGLISSVCCVFGQADENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCHPNDIENPRGSKDIKKNKNVTNRSKGTAEKLQPEDITQIQPQQLVLQLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTNEQNCTSPFSYKNVLSLTDKGEVFNELVGKQRISGNLDSPEGGFDAI. |
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For Research Use Only | Not For Clinical Use.
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