Mouse Anti-Cattle MBD1 Antibody (MO-AB-15401R)
Cat: MO-AB-15401R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO15401R |
Specificity | This antibody binds to Cattle MBD1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011] |
Product Overview | Mouse Anti-Cattle MBD1 Antibody is a mouse antibody against MBD1. It can be used for MBD1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Methyl-CpG binding domain protein 1; MBD1 |
UniProt ID | Q2KIY8 |
Protein Refseq | The length of the protein is 642 amino acids long. The sequence is show below: MAEDWLDCPALGPGWKRREVFRKSGATCGRSDTYYQSPTGDRIRSKVELTRYLGPACDLTLFDFKQGVLCYPSPKAQSLAITSRKRKKPSKPAKARKCQVGPQKSEVRKEAPRDDTKADTDTVPASLPAPGCCENCGISFSGDGTRRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGECTACQVKEDCGACSTCLLQLPHDVASGLFCKCERRRCLRIVERSRGCGVCRGCQTREDCGRCRVCLRPPRPGLRRQW. |
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For Research Use Only | Not For Clinical Use.
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