Mouse Anti-Cattle MGP Antibody (MO-AB-15746R)
Cat: MO-AB-15746R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO15746R |
Specificity | This antibody binds to Cattle MGP. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Extracellular region or secreted |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia. |
Product Overview | Mouse Anti-Cattle MGP Antibody is a mouse antibody against MGP. It can be used for MGP detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Matrix Gla protein; MGP |
UniProt ID | Q56JX0 |
Protein Refseq | The length of the protein is 134 amino acids long. The sequence is show below: MNLTKAWNPMKSIPSLTGETLTALYHHNRDGEQKPKRESENSTSLNTSSTGKLVMTSNFANAMPWCMDTMLPTTVISGSAEGPNETGQKSLSRAWCLVLYSLAVALLNYIETYESLNCSLNVLVWLHPSFLPTG. |
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For Research Use Only | Not For Clinical Use.
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