Mouse Anti-Cattle OSBP Antibody (MO-AB-17356R)


Cat: MO-AB-17356R
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
CloneMO17356R
SpecificityThis antibody binds to Cattle OSBP.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Golgi apparatus; Cytosol; Nucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionLipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum (By similarity). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol (PubMed:18165705). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly (By similarity). Regulates cholesterol efflux by decreasing ABCA1 stability (By similarity).
Product OverviewThis product is a mouse antibody against OSBP. It can be used for OSBP detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesOxysterol-binding protein, Fragment; OSBP
UniProt IDE1BPW1
Protein RefseqThe length of the protein is 692 amino acids long.
The sequence is show below: RSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQNTLRTLSSKVEDLSTCNDLIAKHGTALQRSLSELEALRLPAESSEKIKQVNERATLFRITSNAMINACRDFLVLAQTHSKKWQKSLQYERDQRIRLEETLEQLAKQHNHLERAFRGATVLPAGAPGAGPGKDQSCSGKGDLSDEDDENEFFDAPEIITVLIFILIPV.
See other products for " OSBP "
MO-AB-42253WMouse Anti-Guinea pig OSBP Antibody (MO-AB-42253W)
CBMOAB-53598FYAMouse Anti-Rhesus OSBP Antibody (CBMOAB-53598FYA)
MO-AB-28050RMouse Anti-Pig OSBP Antibody (MO-AB-28050R)
MO-AB-08978WMouse Anti-Cat OSBP Antibody (MO-AB-08978W)
MO-AB-35346WMouse Anti-Ferret OSBP Antibody (MO-AB-35346W)
MO-DKB-01061WRabbit Anti-OSBP Antibody (MO-DKB-01061W)
MO-AB-11145WMouse Anti-Chimpanzee OSBP Antibody (MO-AB-11145W)
MO-AB-09247YMouse Anti-Rabbit OSBP Antibody (MO-AB-09247Y)
MO-AB-38693WMouse Anti-Gorilla OSBP Antibody (MO-AB-38693W)
MO-AB-33556HMouse Anti-Nile tilapia OSBP Antibody (MO-AB-33556H)
For Research Use Only | Not For Clinical Use.
Online Inquiry