Mouse Anti-Cattle TCF4 Antibody (MO-AB-21362R)


Cat: MO-AB-21362R
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
CloneMO21362R
SpecificityThis antibody binds to Cattle TCF4.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box (''E-box'') binding site (''CANNTG'') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to>50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.
Product OverviewThis product is a mouse antibody against TCF4. It can be used for TCF4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesTCF7L2 protein; Transcriptional factor 4; TCF7L2; TCF4
UniProt IDA6QPK5
Protein RefseqThe length of the protein is 647 amino acids long.
The sequence is show below: MFSPPVSSGKNGPTSLASGHFTGSNVEDRSSSGSWGSGGHPSPSRNYGDGTPYDHMTSRDLGSHDNLSPPFVNSRIQSKTERGSYSSYGRESNLQGCHQQSLLGGDMDMGNPGTLSPTKPGSQYYQYSSNNPRRRPLHGSTLEVQTKKVRKVPPGLPSSVYAPSASTADYNRDSPGYPSSKPAASTFPSSFFMQDGHHSSDPWSSSSGMNQPGYGGMLGNSSHIPQSSSYCSLHPHERLGYPSHSSADINSSLPP.
For Research Use Only | Not For Clinical Use.
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