Mouse Anti-Cattle TRMT112 Antibody (MO-AB-22205R)


Cat: MO-AB-22205R
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
CloneMO22205R
SpecificityThis antibody binds to Cattle TRMT112.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionActs as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N7 position of a guanine in 18S rRNA (By similarity). The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on ''Gln-185'', using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (By similarity). Involved in the pre-rRNA processing steps leading to small-subunit rRNA production (By similarity). Together with methyltransferase METTL5, specifically methylates the 6th position of adenine in position 1832 of 18S rRNA (By similarity).
Product OverviewThis product is a mouse antibody against TRMT112. It can be used for TRMT112 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMultifunctional methyltransferase subunit TRM112-like protein; tRNA methyltransferase 112 homolog; TRMT112
UniProt IDQ2KIA2
Protein RefseqThe length of the protein is 125 amino acids long.
The sequence is show below: MRLLTHNLLSSHVRGVGPRGFPLRLQATEVRINPVEFNPDFIVRMIPKVEWAALLEAADHLHLIQVPKEPIQGYEHNEEFLRKMHHVLLEVEVLEGTLQCPESGRVFPISRGIPNMLLSDEETET.
For Research Use Only | Not For Clinical Use.
Online Inquiry