Mouse Anti-CAV-1 Antibody (MOFY-0522-FY213)


Cat: MOFY-0522-FY213
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Lot Number

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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MOFY-0522-FY213 Monoclonal Canine, C. elegans (Caenorhabditis elegans) Neut 100 µg
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MO-NAB-00531W Monoclonal C. elegans (Caenorhabditis elegans) IF, WB NW0453 100 µg
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Specifications

Host speciesMouse
Species ReactivityCanine, C. elegans (Caenorhabditis elegans)
FormatLiquid or Lyophilized
BufferPBS
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationNeut
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionThe scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Alternative NamesCaveolin-1; cav-1
For Research Use Only | Not For Clinical Use.
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