Mouse Anti-Chicken FAR1 Antibody (MO-AB-01850Y)
Cat: MO-AB-01850Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Chicken (Gallus gallus) |
Clone | MO01850Y |
Specificity | This antibody binds to Chicken FAR1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. |
Product Overview | This product is a mouse antibody against FAR1. It can be used for FAR1 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | FAR-1 protein; FAR-1 |
UniProt ID | Q90842 |
Protein Refseq | The length of the protein is 124 amino acids long. The sequence is show below: TISWRRADGKQIPRKARRHRSNGLLEIPNFQQEDAGLYECVAENVRGKNVARGQLTFYAQPNWIQKISDVHAAIEENVFWECHASGRPKPSYRWLKDGEPLLPQGRVQIEQGSLTIRNVSLSDA. |
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For Research Use Only | Not For Clinical Use.
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