Mouse Anti-CLK2 Antibody (CBMOAB-01821HCB)


Cat: CBMOAB-01821HCB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-01821HCB Monoclonal C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Rhesus (Macaca mulatta) WB, ELISA MO01821HB 100 µg
CBMOAB-39397FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO39397FYA 100 µg
MO-AB-02473H Monoclonal Frog (Xenopus laevis) WB, ELISA MO02473C 100 µg
MO-AB-03535W Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO03535W 100 µg
MO-AB-21514W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO21514W 100 µg
MO-AB-53171W Monoclonal Marmoset WB, ELISA MO53171W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Rhesus (Macaca mulatta)
CloneMO01821HB
SpecificityThis antibody binds to C. elegans CLK2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
Product OverviewMouse Anti-C. elegans CLK2 Antibody is a mouse antibody against CLK2. It can be used for CLK2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesTelomere length regulation protein clk-2; Clock abnormal protein 2; clk-2
UniProt IDQ95YE9
Protein RefseqThe length of the protein is 877 amino acids long. The sequence is show below: MNLRSRLVNATERAVLFQIFKDVQNDPEKYDNAVEAICESIDYFGKFLTDSEYLTQIKPILDTQCPTKSIICFSKCLTKVSTDINTTTFRDVITMLDWLKYVVEKSLTSAICSSLKVKETDVSAVQLYREFASACSNIPEKVSNCCAKALSGEHVKYINTVKWIFKMNLVQGIQKAMLLAHDDIVTAAPFTSFYGSGGPYMKTVAEIISSGRNIDITNKDGLLVQMIEWIGSLNNFDSQWRRMMFLIFQEPTYQGIQVHESLLTTLFLISKSDQILKRCIEATDLTGTLKRVVMVKLPFQRVLKRKTIEILINFVYRTKEQFAIQLLETSVKIWSDLNYAKSAPESQERHIVRMILYLVHLFRTCSSIDWESLFLNSMDGVHCRMSMLPMYVQSGIFVNQALCKQATKHRSKTHGSDEQPPETLEENKFVSSEVGKIWFEEMTSILEHGFNSSTVKDSERVRETANEITKDDSGEEFEETNAQRLQNNKDSAAITSKNNLRLDSDDDEDFPDYQVNESEKIFKNLEIGEEPKNKVTPPAYIADAFEMLLEKEKYEVFEAAFFNITNLINRRPIGFPQIAEKLFIRILHLQNNFGTPKFKETVDEIAVACITQRPEIVPSVVRLIIAPGQGFSIKQRLLHYIHNAADGMGALDKKLEECVMAQQLRIGGPTLSIILHRTINTDYDDEDEDPHRLLVPEWRRMVDARIAANTRRIGTTREPPRAGVVNRLAQAAKYMFYPLLVLPRGENASLLGKDSDLLASLIMVASMVYVRCGVCPQIHRMSSELISYATPHRFSENAKLRTACIIAHLNVTTLLPGDLMDELFDVPALIGWFDWANSVLVNASSSQLEKDMTRQFGHSVTKHLQRYHPAVLQHQDV.
For Research Use Only | Not For Clinical Use.
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