Mouse Anti-COQ8 Antibody (CBMOAB-00795CR)

Cat: CBMOAB-00795CR

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-00795CR	Monoclonal	Yeast, C. elegans (Caenorhabditis elegans)	WB, ELISA	MO00795CR		100 µg	Inquiry
Protein Refseq: The length of the protein is 501 amino acids long. The sequence is show below: MVTNMVKLRNLRRLYCSSRLLRTIQNGRISSVSSISLSKKYTTKSAKEGEENVERKHEEEKKDTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAKGNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV.
CBMOAB-02097HCB	Monoclonal	C. elegans (Caenorhabditis elegans)	WB, ELISA	MO02097HB		100 µg	Inquiry
Protein Refseq: The length of the protein is 755 amino acids long. The sequence is show below: MAAKRPPASTLKWCQQEMGPICEGIGMVVRSQIGYDGRRIEKQIRRKALQTVVMGGQDVDPLKEPNKTNAPLLSPTLPSTNEALQRARVVAAGIETFAKLMSQGTYPGSAGFTVSETGERKYMKQTSPVQSNIVANLMATADKLSKGVISLAPFPLPTITKLGTWVIANPTAQLPIPPQLKSAIPAIGQIETLIQSILGVQGPVSSVSRAPRKLKLEGVTDQVVLEPETIHATVDVEPIDKTLTKEEAEFLIKAARSVDDDNAETAIFGTQKAKPKVYRPELPKNFEVNLEMGNVHTLTRSNESSVPATRIGRLATFGQLAFGLLGGATAEVTRRTFGIGKRLQEEGIPKNPFLSEANADRIVATLCRVRGAALKLGQMLSIQDSSTVPPALLQIFERVRQSADFMPIKQVHRQMKDAFGDDWREKFEHFDDKPFACASIGQVHKAVLKDGRNVAVKVQYPGVAEGIDSDIDNLVSVLSVGGIFPKGMFLDAFVGVARRELKQECDYEREARAMKKFRELIADWQDVYVPEVIDELSSSRVLTTELVYGKPVDACVEEPQVVRDYIAGKFIELCLKEIFLWRFMQTDPNWSNFFLGKHPKTGEPRLVLLDFGASRAYGKKFVDIYMNIIKSAYDGDKKKIIEYSREIGFLTGYETSVMEDAHVESVMIMGETLASNHPYNFANQDVTMRIQKLIPVMLEHRLTSPPEEIYSLHRKLSGCYLLAAKLKATVSCGGLFHEIHENYVFGEDGIDINID.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Yeast, C. elegans (Caenorhabditis elegans)
Clone	MO00795CR
Specificity	This antibody binds to Yeast COQ8.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Mitochondrion

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294). Affects the molecular organization and function of COQ3, possibly through kinase activity towards COQ3, COQ5 and/or COQ7 (PubMed:11279158, PubMed:15063807, PubMed:1648478, PubMed:18801050, PubMed:19002377, PubMed:21296186, PubMed:9210471, PubMed:9266513, PubMed:25498144). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity).
Product Overview	Mouse Anti-Yeast COQ8 Antibody is a mouse antibody against COQ8. It can be used for COQ8 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Probable serine/threonine-protein kinase COQ8, mitochondrial; EC 2.7.11; Activity of bc1 complex protein 1; Coenzyme Q protein 8; Ubiquinone biosynthesis protein COQ8; COQ8; ABC1; YGL119W
UniProt ID	P27697
Protein Refseq	The length of the protein is 501 amino acids long. The sequence is show below: MVTNMVKLRNLRRLYCSSRLLRTIQNGRISSVSSISLSKKYTTKSAKEGEENVERKHEEEKKDTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAKGNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV.

For Research Use Only | Not For Clinical Use.

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