Mouse Anti-CSN1 Antibody (CBMOAB-02210HCB)


Cat: CBMOAB-02210HCB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-02210HCB Monoclonal C. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), O. anatinus (Ornithorhynchus anatinus) WB, ELISA MO02210HB 100 µg
CBMOAB-26862FYC Monoclonal A. thaliana (Arabidopsis thaliana) WB, ELISA MO26862FC 100 µg
MO-AB-06392Y Monoclonal O. anatinus (Ornithorhynchus anatinus) WB, ELISA MO06392Y 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), A. thaliana (Arabidopsis thaliana), O. anatinus (Ornithorhynchus anatinus)
CloneMO02210HB
SpecificityThis antibody binds to C. elegans CSN1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionEssential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in embryogenesis and oogenesis and is required to regulate microtubule stability in the early embryo. Mediates mei-3/katanin targeting for degradation at the meiosis to mitosis transition via deneddylation of cul-3.
Product OverviewMouse Anti-C. elegans CSN1 Antibody is a mouse antibody against CSN1. It can be used for CSN1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCOP9 signalosome complex subunit 1; Signalosome subunit 1; csn-1
UniProt IDQ9GS00
Protein RefseqThe length of the protein is 601 amino acids long. The sequence is show below: MQNELLDDPMDTGAPAAEAAAADEPLPPAHGIDREVTPKPAGNPDLMQQSLDNPAIPMHLIEKRDDRRESCDDGYSLTVNESAIDIESLACSYDSNAFFLRARFIARHCPILRADAYISLINYLKEHTTDITHYVAFFNELESELARKEFKNRQLNFQIPLRDQKWIEENGATWQSTTDQLQAEYKRHKDEGVKESTRRAMEDLFQHYMMAGKIDEAIRLYSRGIRDYCTQLKHSINMWINWMEVAICANDWGKLDTVTNTAYRSLKDADDAEKNSQQSQQAPPQRGENAPYMVERDPNAPIQTLTNRQLIETALAKCLAAQVLLKLRNKRYSQVVETILQIKTECLQSKWFVTSSDLGIYGMLSAMATMSRADLKLQVSGNGTFRKLLESEPQLIELLGSYTSSRFGRCFEIMRSVKPRLLLDPFISRNVDELFEKIRQKCVLQYLQPYSTIKMATMAEAVGMSSAELQLSLLELIEQKHVSLKIDQNEGIVRILDERDENAILKRVNVTCDRATQKAKSLLWKTTLAGANIHSISDKETRPKRKNQKESAKFDRNFGGIDVDEDPRGIAGPSGLSDDFNIAYDQQPQQQVQYLEDLGDI.
For Research Use Only | Not For Clinical Use.
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