Mouse Anti-CYP1A2 Antibody (MO-AB-00286L)
Cat: MO-AB-00286L
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| MO-AB-00286L | Monoclonal | Elephant (Loxodonta africana), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Guinea pig (Cavia porcellus), Horse (Equus caballus), Marmoset, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries) | WB, ELISA | MO00286L | 100 µg | ||
| MO-AB-07933W | Monoclonal | Cat (Felis catus) | WB, ELISA | MO07933W | 100 µg | ||
| MO-AB-12714W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO12714W | 100 µg | ||
| MO-AB-29995W | Monoclonal | Dog (Canis lupus familiaris) | WB, ELISA | MO29995W | 100 µg | ||
| MO-AB-41506W | Monoclonal | Guinea pig (Cavia porcellus) | WB, ELISA | MO41506W | 100 µg | ||
| MO-AB-44260W | Monoclonal | Horse (Equus caballus) | WB, ELISA | MO44260W | 100 µg | ||
| MO-AB-53829W | Monoclonal | Marmoset | WB, ELISA | MO53829W | 100 µg | ||
| MO-AB-11034R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO11034R | 100 µg | ||
| MO-AB-25012R | Monoclonal | Pig (Sus scrofa) | WB, ELISA | MO25012R | 100 µg | ||
| MO-AB-01491Y | Monoclonal | Chicken (Gallus gallus) | WB, ELISA | MO01491Y | 100 µg | ||
| MO-AB-07776Y | Monoclonal | Rabbit (Oryctolagus cuniculus) | WB, ELISA | MO07776Y | 100 µg | ||
| MO-AB-14803Y | Monoclonal | Sheep (Ovis aries) | WB, ELISA | MO14803Y | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Elephant (Loxodonta africana), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Guinea pig (Cavia porcellus), Horse (Equus caballus), Marmoset, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries) |
| Clone | MO00286L |
| Specificity | This antibody binds to Elephant CYP1A2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2. Metabolizes cholesterol toward 25-hydroxycholesterol, a physiological regulator of cellular cholesterol homeostasis. May act as a major enzyme for all-trans retinoic acid biosynthesis in the liver. Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid. Primarily catalyzes stereoselective epoxidation of the last double bond of polyunsaturated fatty acids (PUFA), displaying a strong preference for the (R,S) stereoisomer. Catalyzes bisallylic hydroxylation and omega-1 hydroxylation of PUFA. May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent). Plays a role in the oxidative metabolism of xenobiotics. Catalyzes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. Metabolizes caffeine via N3-demethylation. |
| Product Overview | This product is a mouse antibody against CYP1A2. It can be used for CYP1A2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Cytochrome P450 Family 1 Subfamily A Member 2; Cytochrome P450, Subfamily I (Aromatic Compound-Inducible), Polypeptide 2; Cytochrome P450, Family 1, Subfamily A, Polypeptide 2; Cholesterol 25-Hydroxylase; Cytochrome P(3)450; Cytochrome P450-P3; Cytochrome P450 4; EC 1.14.14.1; CYPIA2; Flavoprotein-Linked Monooxygenase |
| UniProt ID | G3UID3 |
| Protein Refseq | The length of the protein is 516 amino acids long. The sequence is show below: IKMVLSQSVPFSATEFLLAFVIFCLMFWVIRAWKPQVPKGLKSPPGPWGWPLIGHVLTLGRNPHLALTRLSQQYGDVMQVRIGSTPVLVLSGLDTIQQALVQQGDDFKGRPDLYSSTLINDGQSMTFSPDSGPVWAARRRLAQKALNTFSMASDPASLSSCYLEEHVINEAEALLHRLQELMAGAGGFDPYSQVVVSVTNIIGAMCFGQHFPQHSEELLSLIENTHEFVETATSGNPMDFFPFLRYLPSPALQKFKVFNQRFLQFVQKTVQGHYRDFDKNSVQDITGALFKHSEEGSRASGGLMPQKKIINLVNDIFGAGIDTVTTAISWSLMYLMTKPGIQKKIQKELDTVIGKARKPRLSDRPQLPYMEAFILEIFRHSSFVPFTIPHSTTRDTTLNGLYIPKGRCVFVNQWHVNHDQKLWGDPFEFRPERFLTAEGSTINKTLSEKVMLFGMGKRRCIGEVLAKCEIFLFLAILLQQLEFSLPPGIKVDLTPTYGLTMKHARCKHVQAQLRFS. |
For Research Use Only | Not For Clinical Use.
Online Inquiry